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The latentiation process in drug design.
(Soc Brasileira Quimica, 1999-01-01)
Short review about the main aspects of prodrug design, as its objectives, applicability and importance, showing the new trends in the research for selective latent forms, namely targeted drugs.
Molecular design and structural optimization of nanocellulose-based films fabricated via regioselective functionalization for flexible electronics
(2022-07-15)
Nanocellulose backbones highly regioselectively substituted with thiophene and long fatty acid side chains were synthesized via a protecting group strategy. The presence of long-chain pendants balanced the torsional ...
Pharmacological Evaluation and Preliminary Pharmacokinetics Studies of a New Diclofenac Prodrug without Gastric Ulceration Effect
(Mdpi Ag, 2012-11-01)
Long-term nonsteroidal anti-inflammatory drugs (NSAIDs) therapy has been associated with several adverse effects such as gastric ulceration and cardiovascular events. Among the molecular modifications strategies, the prodrug ...
Pharmacological Evaluation and Preliminary Pharmacokinetics Studies of a New Diclofenac Prodrug without Gastric Ulceration Effect
(Mdpi Ag, 2012-11-01)
Long-term nonsteroidal anti-inflammatory drugs (NSAIDs) therapy has been associated with several adverse effects such as gastric ulceration and cardiovascular events. Among the molecular modifications strategies, the prodrug ...
Chemical modification of graphene via hyperthermal molecular reaction
(2014)
Chemical functionalization of graphene is achieved by hyperthermal reaction with azopyridine molecular ions. The one-step, room temperature process takes place in high vacuum (10–7 mbar) using an electrospray ion beam ...
Structural Model for the Spider Silk Protein Spidroin-1
(Amer Chemical Soc, 2015-09-01)
Most reports about the 3-D structure of spidroin-1 have been proposed for the protein in solid state or for individual domains of these proteins. A gel-based mass spectrometry strategy using collision-induced dissociation ...
Emerging role of dynamic RNA modifications during animal development
(Elsevier Science, 2018-12)
The central dogma of molecular biology statically says that the information flows from DNA to messenger RNA to protein. But the recent advances in mass spectrometry and high throughput technology have helped the scientists ...
Surface modification of polymeric materials by cold atmospheric plasma jet
(Elsevier B.V., 2015)
Surface modification of polymeric materials by cold atmospheric plasma jet
(Elsevier B.V., 2015)