Now showing items 61-70 of 415
Phosphorylation of Mitogen-Activated Protein Kinases Contributes to Interferon γ Production in Response to Mycobacterium tuberculosis
(Oxford University Press, 2012-12)
Immune control of Mycobacterium tuberculosis depends on interferon γ (IFN-γ)–producing CD4+ lymphocytes. Previous studies have shown that T cells from patients with tuberculosis produce less IFN-γ, compared with healthy ...
Mitogen-activated protein kinases and nuclear factor-kappaB participation in skeletal muscle response to oxidative stress in rats with heart failure
(Oxford University Press, 2011-08-01)
Influence of angiotensin-II type 1 receptor blockade on mitogen-activated protein kinases in myocardium of obese rats
(Oxford University Press, 2012-08-01)
p38 MAPK regulates IL-1β induced IL-6 expression through mRNA stability in osteoblasts
Osteoblast-derived IL-6 functions in coupled bone turnover by supporting osteoclastogenesis favoring bone resorption instead of bone deposition. Gene regulation of IL-6 is complex occurring both at transcription and ...
Overexpression of Mitogen-activated protein kinase phosphatase-3 (MKP-3) reduces FoxO1 phosphorylation in mice hypothalamus
The mitogen-activated kinase phosphatase-3 (MKP-3) has gained great importance in the scientific community by acting as a regulator of the cell cycle through dephosphorylation of FoxO1, an important transcription factor ...
Lack of evidence for regulation of cardiac P-type ATPases and MAP kinases in transgenic mice with cardiac-specific overexpression of constitutively active α1B-adrenoceptors
(Associação Brasileira de Divulgação Científica, 2010-05-01)
The regulatory function of α1B-adrenoceptors in mammalian heart homeostasis is controversial. The objective of the present study was to characterize the expression/activity of key proteins implicated in cardiac calcium ...
Potent anti-inflammatory effects of systemically administered curcumin modulate periodontal disease in vivo
Background and Objective:Curcumin is a plant-derived dietary spice with various biological activities, including anticarcinogenic and anti-inflammatory effects. Its therapeutic applications have been studied in a variety ...
Extracellular Signal-Regulated Kinase 1/2 Activation, via Downregulation of Mitogen-Activated Protein Kinase Phosphatase 1, Mediates Sex Differences in Desoxycorticosterone Acetate-Salt Hypertension Vascular Reactivity
(LIPPINCOTT WILLIAMS & WILKINS, 2010)
Extracellular signal-regulated kinase (ERK) 1/2 has been reported to play a role in vascular dysfunction associated with mineralocorticoid hypertension. We hypothesized that, compared with female rats, an upregulation of ...