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Cholesterol in brain disease: sometimesdeterminant and frequently implicated
(Nature Publishing Group, 2014-09)
Cholesterol is essential for neuronal physiology, both during development and in the adult life: as a major component of cell membranes and precursor of steroid hormones, it contributes to the regulation of ion permeability, ...
Investigation of inborn errors of metabolismInvestigação de erros inatos do metabolismo
(HCPA/FAMED/UFRGS, 2022)
Nonalcoholic fatty liver disease and metabolic syndrome: Shared genetic basis of pathogenesis
(John Wiley & Sons Inc, 2016-11)
A growing body of evidence indicates that nonalcoholic fatty liver disease (NAFLD) develops from a complex process that includes genetic susceptibility and environmental exposure. Regardless of whether it is the cause or ...
La biopsia hepática
(Instituto Nacional de Pediatría, 2008)
Plasma soluble erythropoietin receptor is decreased during sleep in Andean highlanders with Chronic Mountain Sickness
(American Physiological Society, 2016)
Excessive erythrocytosis (EE) is the main sign of Chronic Mountain Sickness (CMS), a highly prevalent syndrome in Andean highlanders. Low pulse O2 saturation (SpO2) during sleep and serum androgens have been suggested to ...
Hair follicle characteristics as early marker of Type 2 Diabetes
(Elsevier, 2016)
Type 2 Diabetes mellitus (DM2) includes a continuum of metabolic disorders characterized by hyperglycemia that causes several chronic long-term complications such as coronary artery disease, peripheral arterial disease, ...
Biopsia de nervio periférico
(Instituto Nacional de Pediatría, 2009)
Metabolic profiling reveals that PNPLA3 induces widespread effects on metabolism beyond triacylglycerol remodeling in Huh-7 hepatoma cells
(American Physiological Society, 2014-07)
PNPLA3 was recently associated with the susceptibility to nonalcoholic fatty liver disease, a common cause of chronic liver disease characterized by abnormal triglyceride accumulation. Although it is established that PNPLA3 ...
Use of m-Health Technology for Preventive Interventions to Tackle Cardiometabolic Conditions and Other Non-Communicable Diseases in Latin America- Challenges and Opportunities
(Elsevier, 2016)
In Latin America, cardiovascular disease (CVD) mortality rates will increase by an estimated 145% from 1990 to 2020. Several challenges related to social strains, inadequate public health infrastructure, and underfinanced ...
Overweight and obesity: a review of their relationship to metabolic syndrome, cardiovascular disease, and cancer in South America
(Wiley, 2013-03)
Socioeconomic and demographic transformations are occurring very rapidly in some areas of the world, especially in South America, and are accompanied by changes in lifestyle, dietary patterns, and the epidemiological profile ...