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2,4-dihydroxy benzaldehyde derived Schiff bases as small molecule Hsp90 inhibitors: rational identification of a new anticancer lead
(Elsevier Science, 2015-04)
Hsp90 is a molecular chaperone that heals diverse array of biomolecules ranging from multiple oncogenic proteins to the ones responsible for development of resistance to chemotherapeutic agents. Moreover they are over-expressed ...
Comparative study of cytotoxic and genotoxic effects induced by herbicide S-metolachlor and its commercial formulation Twin Pack Gold® in human hepatoma (HepG2) cells
(Elsevier, 2013-10)
The in vitro effects of S-metolachlor and its formulation Twin Pack Gold® (96% a.i.) were evaluated in human hepatoma (HepG2) cells. Cytokinesis-blocked micronucleus cytome (CBMN-cyt) and MTT assays as well as Neutral Red ...
Carbamates: a study on genotoxic, cytotoxic, and apoptotic effects induced in Chinese hamster ovary (CHO-K1) cells
(Elsevier, 2015-08)
In vitro effects of the carbamates pirimicarb and zineb and their formulations Aficida® (50% pirimicarb) and Azzurro® (70% zineb), respectively, were evaluated in Chinese hamster ovary (CHO-K1) cells. Whereas the ...
Genotoxicity induced by nerol, an essential oil present in citric plants using human peripheral blood mononuclear cells (PBMC) and HepG2/C3A cells as a model
(2021-01-01)
Nerol (cis-3,7-dimethyl-2,6-octadien-1-ol) is a monoterpene widely used in cosmetic products, household detergents and cleaners, as well as a flavoring in several food products. Despite the high level of human exposure to ...
Cytotoxicity of derivatives from dehydrocrotonin on V79 cells and Escherichia coli
(Elsevier Ireland LtdClareIrlanda, 2001)
Synthesis of Ca-doped spinel by ultrasonic spray pyrolysis
(ElsevierAmsterdam, 2016)
MgAl2O4 is a stable catalyst support with potential for replacing gamma-alumina in several applications. However, synthesis of magnesium spinel requires elevated temperatures to avoid phase separation (in MgO and Al2O3) ...
Cryptomoschatone D2 from Cryptocarya mandioccana: cytotoxicity against human cervical carcinoma cell lines
(Universidade Estadual Paulista (Unesp), 2009)
Among the substances isolated from Cryptocarya sp, some styrylpyrones, such as goniothalamin, demonstrate antiproliferative activity in a broad range of human cell lines. In the present study, we assessed the cytotoxicity ...
Susceptibility of Mycobacterium tuberculosis to first-line antimycobacterial agents in a Brazilian hospital: assessing the utility of the tetrazolium (MTT) microplate assay
(Instituto Oswaldo Cruz, Ministério da Saúde, 2010)
Cytotoxicity and genotoxicity of calcium silicate-based cements on an osteoblast lineage
(2016-05-20)
Several calcium silicate-based biomaterials have been developed in recent years, in addition to Mineral Trioxide Aggregate (MTA). The aim of this study was to evaluate the cytotoxicity, genotoxicity and apoptosis/necrosis ...