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Cardiovascular disease is associated with high-fat-diet-induced liver damage and up-regulation of the hepatic expression of hypoxia-inducible factor 1α in a rat model
(Portland Press, 2013-01)
CVD (cardiovascular disease) is associated with abnormal liver enzymes, and NAFLD (non-alcoholic fatty liver disease) is independently associated with cardiovascular risk. To gain insights into the molecular events underlying ...
Liver protective effects of extra virgin olive oil: interaction between Its chemical composition and the cell-signaling pathways involved in protection
(Bentham Science Publ LTD, 2018)
Background and Objective: The liver is an organ susceptible to a multitude of injuries that causes liver damage, like steatosis, non-alcoholic steatohepatitis, cirrhosis, hepatocellular carcinoma, and ischemia-reperfusion ...
Histopathology aspects and fibrosis evaluation of bovine naturally infected livers by Fasciola hepatica
(2014-01-01)
Fasciolosis is a zoonotic disease that infects especially ruminants and the liver damages in chronic infection caused by the parasite are very severe. The aim of this study was to evaluate the histopathological findings ...
Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage
(2021)
Niemann-Pick type C disease (NPCD) is a lysosomal storage disorder caused by mutations in the NPC1 gene. The most affected tissues are the central nervous system and liver, and while significant efforts have been made to ...
Complement Component C3 Participates in Early Stages of Niemann-Pick C Mouse Liver Damage
(MDPI AG, 2020)
Niemann-Pick type C (NPC), a lysosomal storage disorder, is mainly caused by mutations in the NPC1 gene. Niemann-Pick type C patients and mice show intracellular cholesterol accumulation leading to hepatic failure with ...
Administration of multipotent mesenchymal stromal cells restores liver regeneration and improves liver function in obese mice with hepatic steatosis after partial hepatectomy
(BioMed Central Ltd., 2017)
© 2017 The Author(s). Background: The liver has the remarkable capacity to regenerate in order to compensate for lost or damaged hepatic tissue. However, pre-existing pathological abnormalities, such as hepatic steatosis ...
A description of liver and blood changes in matrinxã (Brycon amazonicus) during induced spawning
(2018-10-01)
We investigated the effects of induced spawning on liver and blood cell changes in matrinxã breeders, a commercially valuable South American fish that requires hormonal manipulation and stripping to spawn, a trait shared ...
Nutritional status of alcoholic patients : Its possible relationship to alcoholic liver damage
(1983)
This study was performed to look for a possible relationship between the nutritional status and the presence of liver damage in alcoholic patients. One hundred chronic alcoholics admitted for treatment to the Alcoholism ...
Retinol binding protein 4 and retinol in steatotic and nonsteatotic rat livers in the setting of partial hepatectomy under ischemia/reperfusion
(WILEY-BLACKWELLHOBOKEN, 2012)
Steatotic livers show increased hepatic damage and impaired regeneration after partial hepatectomy (PH) under ischemia/reperfusion (I/R), which is commonly applied in clinical practice to reduce bleeding. The known function ...
Gadolinium Chloride Rescues Niemann–Pick Type C Liver Damage
(2018)
Niemann–Pick type C (NPC) disease is a rare neurovisceral cholesterol storage disorder
that arises from loss of function mutations in the NPC1 or NPC2 genes. Soon after birth, some patients present with an aggressive ...