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The Kallikrein Inhibitor from Bauhinia bauhinioides (BbKI) shows antithrombotic properties in venous and arterial thrombosis models
(Elsevier B.V., 2014-05-01)
The Bauhinia bauhinioides Kallikrein Inhibitor (BbKI) is a Kunitz-type serine peptidase inhibitor of plant origin that has been shown to impair the viability of some tumor cells and to feature a potent inhibitory activity ...
Molecular cloning and structural modelling of gamma-phospholipase A2 inhibitors from Bothrops atrox and Micrurus lemniscatus snakes
(2017-10-01)
Phospholipases A2 inhibitors (PLIs) produced by venomous and non-venomous snakes play essential role in this resistance. These endogenous inhibitors may be classified by their fold in PLIα, PLIβ and PLIγ. Phospholipases ...
Production of β-lactamase inhibitors by Streptomyces species
(2018-09-01)
β-Lactamase inhibitors have emerged as an effective alternative to reduce the effects of resistance against β-lactam antibiotics. The Streptomyces genus is known for being an exceptional natural source of antimicrobials ...
Tamarind enzymatic inhibitors: activities and health application perspectives
(Food Reviews Internatonal, 2023)
The defensive functions of plant inhibitors are not restricted to insect enzyme inhibition
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
Three plant proteinase inhibitors BbKI (kallikrein inhibitor) and BbCI (cruzipain inhibitor) from Bauhinia bouhinioides, and a BrTI (trypsin inhibitor) from B. rufa, were examined for other effects in Callosobruchus maculatus ...
Direct Oral FXa Inhibitors Binding to Human Serum Albumin: Spectroscopic, Calorimetric, and Computational Studies
(2023)
Direct FXa inhibitors are an important class of bioactive molecules (rivaroxaban, apixaban,edoxaban, and betrixaban) applied for thromboprophylaxis in diverse cardiovascular pathologies.The interaction of active compounds ...
Corrosion protection of steel by volatile corrosion inhibitors: Vapor analysis by gas-diffusion microextraction and mass loss and electrochemical impedance in nacl deliquescence tests
(2020-10-01)
A new methodology using gas-diffusion microextraction (GDME) was developed for the analysis of volatile corrosion inhibitors (VCIs). The evaluation of the inhibition efficiency and corrosion rate (ν) was performed by NaCl ...
Isolation and characterization of a new trypsin inhibitor from Crotalaria paulina seeds
(Taylor & Francis IncPhiladelphiaEUA, 1999)