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Hyaluronan preconditioning of monocytes/macrophages affects their angiogenic behavior and regulation of TSG-6 expression in a tumor type-specific manner
(Wiley Blackwell Publishing, Inc, 2019-05)
Hyaluronan is a glycosaminoglycan normally present in the extracellular matrix in most tissues. Hyaluronan is a crucial player in many processes associated with cancer, such as angiogenesis, invasion and metastasis. However, ...
Do filamentous fungi synthesize hyaluronan?
(XI CONGRESO NACIONAL DE BIOLOGÍA MOLECULAR Y CELULAR DE HONGOS, 2015)
Serum laminin, type IV collagen and hyaluronan as fibrosis markers in non-alcoholic fatty liver disease
(Associação Brasileira de Divulgação Científica, 2005-05-01)
Hepatic fibrosis in patients with non-alcoholic fatty liver disease is associated with progression of the disease. In the present study, we analyzed the discriminative ability of serum laminin, type IV collagen and hyaluronan ...
Human leukaemic cell lines synthesize hyaluronan to avoid senescence and resist chemotherapy
(Oxford Univ Press Inc, 2013-11)
Hyaluronan (HA) is one of the major components of the extracellular matrix. Several solid tumors produce high levels of HA, which promotes survival and multidrug resistance (MDR). HA oligomers (oHAs) can block HA effects. ...
Changes of Large Molecular Weight Hyaluronan and Versican in the Mouse Pubic Symphysis Through Pregnancy
(Soc Study ReproductionMadison, 2012)
Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation
(Assoc Research Vision Ophthalmology Inc, 2017)
PURPOSE. Limbal epithelial stem cells (LSCs), located in the basal layer of the corneal epithelium in the corneal limbus, are vital for maintaining the corneal epithelium. LSCs have a high capacity of self-renewal with ...
The scrambled story between hyaluronan and glioblastoma
(American Society for Biochemistry and Molecular Biology, 2021-01)
Advances in cancer biology are revealing the importance of the cancer cell microenvironment on tumorigenesis and cancer progression. Hyaluronan (HA), the main glycosaminoglycan in the extracellular matrix, has been associated ...
Hyaluronan oligomers sensitize chronic myeloid leukemia cell lines to the effect of imatinib
(Oxford University Press, 2016-04)
Chronic myeloid leukemia is a myeloproliferative syndrome characterized by the presence of the Philadelphia chromosome (Ph), generated by a reciprocal translocation occurring between chromosomes 9 and 22 [t(9;22)(q34;q11)]. ...