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Genética de la esquizofrenia: avances en el estudio de genes candidatos
(Rev. biol. trop v.52 n.3, p. 467-473 sep. 2004, 2004)
Genetics of Schizophrenia: advances in the study of candidate genes. Schizophrenia is one of the
most severe mental disorders that affect 1% of the population worldwide. It is clear that both genetic and
environmental ...
A biocomputational platform for the automated construction of large-scale mathematical models of miRNA-transcription factor networks for studies on gene dosage compensation
(2016-11-09)
Cancer complexity and resistance is mediated by
cell-to-cell heterogeneity, which is the consequence of the
enormous instability of its genetic material. It is unknown how
cancer cells are able to withstand the effects ...
Transcription analysis of softening-related genes during postharvest of papaya fruit (Carica papaya L. ‘Pococí’ hybrid)
(2017-03)
Fruit of Carica papaya L. (papaya) has several post-harvest problems mainly caused by quick softening that reduces its shelf life. This softening is directly related to degradation and modification of cell wall oligosaccharides. ...
When genes move farther than offspring: gene flow by male gamete dispersal in the highly philopatric bat species Thyroptera tricolor
(2013-11)
For species characterized by philopatry of both sexes, mate selection represents an important behaviour for inbreeding avoidance, yet the implications for gene flow are rarely quantified. Here, we present evidence of male ...
Role of the snake venom toxin jararhagin in proinflammatory pathogenesis: In vitro and in vivo gene expression analysis of the effects of the toxin
(2005-09)
To assess the indirect effects of snake venom metalloproteinases (SVMP) on host tissue local necrosis, we investigated the effect of the SVMP jararhagin on the gene expression profiles of human fibroblasts in vitro and ...
Predominance of carbapenem-resistant Pseudomonas aeruginosa isolates carrying blaIMP and blaVIM metallo-β-lactamases in a major hospital in Costa Rica
(2015)
This study aimed to assess the molecular basis of the resistance to carbapenems in clinical isolates of Pseudomonas aeruginosa recovered from a tertiary-level health facility in San José, Costa Rica. A total of 198 ...
Genetic diversity in Oryza glumaepatula wild rice populations in Costa Rica and possible gene flow from O. sativa
(2016-04-07)
Wild crop relatives are an important source of genetic diversity for crop improvement. Diversity estimates are generally lacking for many wild crop relatives. The objective of the present study was to analyze how genetic ...
Composition and Gene Expression of the cag Pathogenicity Island in Helicobacter pylori Strains Isolated from Gastric Carcinoma and Gastritis Patients in Costa Rica
(Infection Immunity 69 (3) 1902-1908, 2001-03)
The composition and in vitro expression of the cag pathogenicity island genes in a group of Helicobacter pylori strains obtained from patients suffering from chronic gastritis-associated dyspepsia (n = 26) or gastric ...