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Functionalization of stable fluorescent nanodiamonds towards reliable detection of biomarkers for Alzheimer’s disease
(2018)
Abstract
Background
Stable and non-toxic fluorescent markers are gaining attention in molecular diagnostics as powerful tools for enabling long and reliable biological ...
Carbon Monoxide Modulates Connexin Function through a Lipid Peroxidation-Dependent Process: A Hypothesis.
(Lausanne : Frontiers Research Foundation, 2016)
Hemichannels are ion channels composed of six connexins (Cxs), and they have the peculiarity to be permeable not only to ions, but also to molecules such as ATP and glutamate. Under physiological conditions they present a ...
Climate change and plant dispersal along corridors in fragmented landscapes of Mesoamerica
(2013)
Climate change is a threat to biodiversity, and adaptation measures should be
considered in biodiversity conservation planning. Protected areas (PA) are
expected to be impacted by climate change and improving their ...
In vitro plant regeneration and cryopreservation of Arachis glabrata (Fabaceae) using leaflet explants
(Springer, 2017-12)
Arachis glabrata Benth (perennial peanut) is a rhizomatous legume with high forage value and great potential for soil conservation as well as it displays valuable plant genetic resources for the cultivated edible peanut ...
Intrinsic DNA curvature in trypanosomes
(BioMed Central Ltd., 2017)
Background: Trypanosoma cruzi and Trypanosoma brucei are protozoan parasites causing Chagas disease and African sleeping sickness, displaying unique features of cellular and molecular biology. Remarkably, no canonical ...
Free radicals derived from γ-radiolysis of water and AAPH thermolysis mediate oxidative crosslinking of eGFP involving Tyr-Tyr and Tyr-Cys bonds : the fluorescence of the protein is conserved only towards peroxyl radicals
(2020-04)
The enhanced green fluorescent protein (eGFP) is one of the most employed variants of fluorescent proteins. Nonetheless little is known about the oxidative modifications that this protein can undergo in the cellular milieu. ...
How Many Sirtuin Genes Are Out There? Evolution of Sirtuin Genes in Vertebrates With a Description of a New Family Member
(2023-02-01)
Studying the evolutionary history of gene families is a challenging and exciting task with a wide range of implications. In addition to exploring fundamental questions about the origin and evolution of genes, disentangling ...
Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis
(Elsevier, 2019)
Cells evolved robust homeostatic mechanisms to protect against oxidation or alkylation by electrophilic species.
Glutathione (GSH) is the most abundant intracellular thiol, protects cellular components from oxidation and ...