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AT(1) receptor participates in the cardiac hypertrophy induced by resistance training in rats
(AMER PHYSIOLOGICAL SOC, 2008)
Resistance training is accompanied by cardiac hypertrophy, but the role of the renin-angiotensin system (RAS) in this response is elusive. We evaluated this question in 36 male Wistar rats divided into six groups: control ...
Protective actions of human tissue kallikrein gene in transgenic rat hearts
(Elsevier B.V., 2008-02-01)
In this study, we used an experimental model. of cardiac hypertrophy to explore the role of the kallikrein-kinin system (KKS) in cardiac protection in transgenic rats harboring the human tissue kallikrein gene, TGR(hKLK1). ...
Selective increase in cardiac IGF-1 in a rat model of ventricular hypertrophy
(Academic Press Inc., 1998)
There is evidence that insulin-like growth factor-1 (IGF-1) plays a role in the development of left ventricular hypertrophy, but it is uncertain whether cardiac IGP-1 changes before or after hypertension is established, ...
Role of FAK signaling in chagasic cardiac hypertrophy
(Sociedade Brasileira de Infectologia, 2020)
Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro
(Lippincott Williams and Wilkins, 2010)
Background: Angiotensin-(1-9) is present in human and rat plasma and its circulating levels increased early after myocardial infarction or in animals treated with angiotensin-converting enzyme inhibitor. However, the ...
Osteoglycin post-transcriptional regulation by miR-155 induces cellular architecture changes in H9c2 cardiomyoblasts
(Elsevier B.V., 2018-11-15)
Several studies have demonstrated dysregulated cardiac microRNAs (miRNAs) following cardiac stress and development of cardiac hypertrophy and failure. miRNAs are also differentially expressed in the inflammation that occurs ...
Loss of cardiac carnitine palmitoyltransferase 2 results in rapamycin-resistant, acetylation-independent hypertrophy
(American Society for Biochemistry and Molecular Biology, 2017-11)
Cardiac hypertrophy is closely linked to impaired fatty acid oxidation, but the molecular basis of this link is unclear. Here, we investigated the loss of an obligate enzyme in mitochondrial long-chain fatty acid oxidation, ...