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Nuclear Factor (NF) κB polymorphism is associated with heart function in patients with heart failure
(2010)
Abstract
Background
Cardiac remodeling is generally an adverse sign and is associated with heart failure (HF) progression. NFkB, an important transcription factor involved in many cell survival pathways, has been implicated ...
Effects of dipeptidyl-peptidase 4 inhibitor about vascular inflammation in a metabolic syndrome model
(Public Library of Science, 2014-09)
Background
In this study, we used vidagliptin(V) to examine the role of the DDP-IV, incretin system component, in the activation of different molecular inflammatory cytokines, NF-kB and VCAM-1 to generate a microenvironment ...
Blood lactate increases with the progression of mitral valve disease in dogs
(Revista Pesquisa Veterinaria Brasileira, 2018-09-01)
In dogs with congestive heart failure, the upregulated sympathetic tone causes vasoconstriction that impairs peripheral blood supply, therefore causing the accumulation of lactate. In this prospective cross-sectional study ...
Modification of cardiac biomarkers sensity in hypertensive patiens treated with angiotensin-converting enzyme inhibitors in acute coronary syndrome with non-st segment elevation
(International Knowledge Press, 2019-06)
Background: Patients with non-ST segment elevation myocardial infarction and the mortality risk is associated when Creatine Kinase isoenzyme MB and Troponin I values are increase. Objective: The present study was oriented ...
Subclinical Detection of Diabetic Cardiomyopathy with MicroRNAs: Challenges and Perspectives
(Hindawi Publishing Corporation, 2016)
The prevalence of cardiac diabetic diseases has been increased around the world, being the most common cause of death and disability among diabetic patients. In particular, diabetic cardiomyopathy is characterized with a ...
Subclinical Detection of Diabetic Cardiomyopathy with MicroRNAs: Challenges and Perspectives
(Hindawi Publishing Corporation, 2016)
The prevalence of cardiac diabetic diseases has been increased around the world, being the most common cause of death and disability among diabetic patients. In particular, diabetic cardiomyopathy is characterized with a ...
The Cancer Therapy-Related Clonal Hematopoiesis Driver Gene Ppm1d Promotes Inflammation and Non-Ischemic Heart Failure in Mice
(Lippincott Williams, 2021-09)
Rationale: Cancer therapy can be associated with short- and long-term cardiac dysfunction. Patients with cancer often exhibit therapy-related clonal hematopoiesis (t-CH), an aggressive form of clonal hematopoiesis that can ...
Avaliação bioquímica e ecodopplercardiográfica de camundongos Mas-KO submetidos à coarctação da aorta torácica
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia e FarmacologiaUFMG, 2017-10-26)
The heptapeptide angiotensin –(1-7) (Ang – (1-7)) exerts its effects through interaction with Mas
receptor. As a result of this interaction, an essential contra regulatory role of Ang – (1-7) against the
constrictor and ...
The Action of 2-aminoethyldiphenyl borinate on the pulmonary arterial hypertension and remodeling of high-altitude hypoxemic lambs
(Frontiers Media, 2022)
Calcium signaling is key for the contraction, differentiation, and proliferation of pulmonary arterial smooth muscle cells. Furthermore, calcium influx through store-operated channels (SOCs) is particularly important in ...