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Synthetic pregnenolone derivatives as antiviral agents against acyclovir-resistant isolates of Herpes Simplex Virus Type 1
(Elsevier Science, 2015-10)
The conventional therapy for the management of Herpes Simplex Virus Type 1 (HSV-1) infections mainly comprises acyclovir (ACV) and other nucleoside analogues. A common outcome of this treatment is the emergence of resistant ...
Revealing new non-covalent interactions in polymorphs and hydrates of Acyclovir: Hirshfeld surface analysis, NCI plots and energetic calculations
(Elsevier, 2021-03)
An exhaustive evaluation of intermolecular interactions in the four known stable Forms of Acyclovir (ACV), namely, two polymorphs (Forms I and II) and two hydrates (Forms V and VI), is presented completing the descriptions ...
Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir
(Elsevier B.V., 2014)
Determination of elemental impurities in acyclovir ointment and raw materials using microwave acid digestion (MW-AD) and ICP-MS
(2017-01-01)
Inorganic elements present in pharmaceutical products were determined by inductively coupled plasma-mass spectrometer (ICP-MS), employing microwave acid digestion as a sample preparation method. The most abundant isotopes, ...
Infecciones por virus varicela zoster en menores de 15 años con cáncer
(Sociedad Médica de Santiago, 2003)