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Structure-activity relationship of mastoparan analogs: effects of the number and positioning of Lys residues on secondary structure, interaction with membrane-mimetic systems and biological activity
(Elsevier B. V., 2015-05-02)
In this study, a series of mastoparan analogs were engineered based on the strategies of Ala and Lys scanning in relation to the sequences of classical mastoparans. Ten analog mastoparans, presenting from zero to six Lys ...
Delayed onset of electromyographic activity of the vastus medialis relative to the vastus lateralis may be related to physical activity levels in females with patellofemoral pain
(2016-02-01)
The aims of this study were to examine group differences in muscle activation onset of the vastus medialis (VM) in relation to the vastus lateralis (VL) and pain level during stair ascent in females with patellofemoral ...
RNA activation: A diamond in the rough for genome engineers
(Wiley-liss, Div John Wiley & Sons Inc, 2017-06)
The ability to develop efficient and versatile technologies for manipulating gene expression is a fundamental issue both in biotechnology and therapeutics. The endogenous RNA interference (RNAi) pathway which mediates gene ...
A critical analysis on "Active Learning" in the light of Cultural-Historical Activity Theory (CHAT): Implications to Physics Education and to experimental activities as a particular case.
(The International Commission on Physics Education (ICPE) Commission C14 of the International Union of P ure and Applied Physics (IUPAP)The European Physical Society Physics Education Division (EPS PED)The Faculty of Mathematics and Physics, Charles Un iversity in PraguePraga, 2013-08-05)
This is a research paper in which we discuss “active learning” in the light of Cultural-Historical Activity Theory (CHAT), a powerful framework to analyze human activity, including teaching and learning process and the ...
Phytomedicinal potential of tropical cloudforest plants from Monteverde, Costa Rica
(Universidad de Costa Rica, 2003)
A structure-activity relationship study of quinone compounds with trypanocidal activity
(Elsevier B.V., 2005-04-01)
A set of 25 quinone compounds with anti-trypanocidal activity was studied by using the density functional theory (DFT) method in order to calculate atomic and molecular properties to be correlated with the biological ...