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In vivo antileishmanial activity and histopathological evaluation in Leishmania infantum infected hamsters after treatment with a furoxan derivative
(2017-11-01)
N-oxide derivatives compounds such as furoxan and benzofuroxan are promising scaffolds for designing of new antileishmanial drugs. A series of furoxan (1,2,5-oxadiazole 2-N-oxide) (compounds 4a-b, and 14a-f) and benzofuroxan ...
A new nanoemulsion formulation improves antileishmanial activity and reduces toxicity of amphotericin B
(Harwood Academic Publishers, 2019)
A Comparative Study on Chemical Composition, Antileishmanial and Cytotoxic Activities of the Essential Oils from Leaves of Guarea macrophylla (Meliaceae) from Two Different Regions of Sao Paulo State, Brazil, Using Multivariate Statistical Analysis
(Soc Brasileira Quimica, 2019-07-01)
Meliaceae representatives are economically important in several aspects including the production of highly prized woods (mahogany, cedar, etc.), constituents for cosmetics, and insecticides. The present study aimed to ...
Original antileishmanial hits: Variations around amidoximes
(Elsevier, 2018)
Synthesis, cytotoxicity, antibacterial and antileishmanial activities of imidazolidine and hexahydropyrimidine derivatives
(2013-05-01)
This paper describes the synthesis and in vitro biological activities of imidazolidine and hexahydropyrimidine derivatives against bacteria (Escherichia coli, Staphylococcus aureus and Mycobacterium tuberculosis) and ...
Synthesis, cytotoxicity, antibacterial and antileishmanial activities of imidazolidine and hexahydropyrimidine derivatives
(2013-05-01)
This paper describes the synthesis and in vitro biological activities of imidazolidine and hexahydropyrimidine derivatives against bacteria (Escherichia coli, Staphylococcus aureus and Mycobacterium tuberculosis) and ...
Synthesis of 4-aminoquinoline analogues and their platinum(II) complexes as new antileishmanial and antitubercular agents
(Elsevier France-editions Scientifiques Medicales Elsevier, 2011-06-01)
A series of 4-amino-7-chloroquinoline derivatives were synthesized by the reaction of 4,7-dichloroquinoline with the corresponding diamine and then with propargyl bromide. In addition, platinum(II) complexes were obtained ...
Synthesis of 4-aminoquinoline analogues and their platinum(II) complexes as new antileishmanial and antitubercular agents
(Elsevier France-editions Scientifiques Medicales Elsevier, 2011-06-01)
A series of 4-amino-7-chloroquinoline derivatives were synthesized by the reaction of 4,7-dichloroquinoline with the corresponding diamine and then with propargyl bromide. In addition, platinum(II) complexes were obtained ...
Comparative studies of the anti-leishmanial activity of three Crotalus durissus ssp venoms
(Springer, 2007-10-01)
In this study, we compared the anti-leishmanial activity of three crotalic venoms (Crotalus durissus terrificus-Cdt, Crotalus durissus cascavella-Cdca, and Crotalus durissus collilineatus-Cdcol). Different concentrations ...