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Experimental studies and computational modeling on cytochrome c reduction by quercetin: The role of oxidability and binding affinity
(2021-11-15)
Quercetin is a potent reducing agent of cytochrome C (Cyt c). Cyt c plays a fundamental role in the intrinsic apoptotic pathway, and there is evidence of the quercetin's role in this cellular event, which is involved in ...
Quercetin oxidation paradoxically enhances its antioxidant and cytoprotective properties
(American Chemical Society, 2017)
Quercetin oxidation is generally believed to ultimately result in the loss of its antioxidant properties. To test this assertion, quercetin oxidation was induced, and after each of its major metabolites was identified and ...
Quercetin-PVP K25 solid dispersions: Preparation, thermal characterization and antioxidant activity
(Springer, 2011-04-01)
Quercetin is a flavonoid very well studied and has already entered clinical trials emerging as prospective anticancer drug candidate. In addition, quercetin has being reported to its free-radical scavenging activity and ...
Quercetin-PVP K25 solid dispersions: Preparation, thermal characterization and antioxidant activity
(Springer, 2011-04-01)
Quercetin is a flavonoid very well studied and has already entered clinical trials emerging as prospective anticancer drug candidate. In addition, quercetin has being reported to its free-radical scavenging activity and ...
Theoretical Study of the Antioxidant Activity of Quercetin Oxidation Products
(Frontiers Media S.A., 2019)
Quercetin reduces Staphylococcus aureus interaction with neutrophils
(2011-09-01)
Flavonoids, including quercetin, have been reported to modulate the ability of Staphylococcus aureus to adhere to host tissue without exhibiting direct antibacterial activity. In the present study, we evaluated the interaction ...
Effects of quercetin administration on the pregnancy outcome of diabetic rats
(2012)
Objective: Investigate the effects of diabetes and treatment with quercetin on the maternal reproductive performance and impact on foetal growth. Study design: A total of 32 female Wistar rats were distributed into four ...
Low nanomolar concentrations of a quercetin oxidation product, which naturally occurs in onion peel, protect cells against oxidative damage
(Elsevier, 2020)
The occurrence of the quercetin oxidation metabolite 2-(3,4-dihydroxybenzoyl)-2,4,6-trihydroxy-3(2H)-benzofuranone (BZF), whose antioxidant potency is notably higher than the antioxidant potency of quercetin, was investigated ...
Quercetin ameliorates glucose and lipid metabolism and improves antioxidant status in postnatally monosodium glutamate-induced metabolic alterations
(Pergamon-Elsevier B.V. Ltd, 2012-10-01)
We reported the effects of quercetin on metabolic and hormonal profile as well as serum antioxidant activities in a model of MSG (monosodium glutamate)-induced obesity. Rats were divided into 4 groups: MSG group, submitted ...
Quercetin induces lipid domain-dependent permeability
(2022-01-01)
Quercetin is a polyphenolic molecule with a broad spectrum of biological activities derived from its antioxidant property. Its mechanism of action has been explained by its binding and/or interference with enzymes, receptors, ...