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Cytotoxicity of phenothiazine derivatives associated with mitochondrial dysfunction: A structure-activity investigation
(Elsevier B.V., 2015-04-01)
Phenothiazine derivatives are neuroleptic drugs used in the treatment of schizophrenia and anxiety. Several side effects are described for these drugs, including hepatotoxicity, which may be related to their cytotoxic ...
Continuous photometric method for the screening of human urines for phenothiazines
(Elsevier Science BvAmsterdamHolanda, 2002)
NEW SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF PHENOTHIAZINE DERIVATIVES
(Associação Brasileira de Divulgação Científica (ABRADIC), 1978-01-01)
NEW SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF PHENOTHIAZINE DERIVATIVES
(Associação Brasileira de Divulgação Científica (ABRADIC), 1978-01-01)
In vitro human plasma leucine5-enkephalin degradation is inhibited by a select number of drugs with the phenothiazine molecule in their chemical structure
(2003)
A number of drugs with the phenothiazine molecule in their chemical structure inhibit in a dose-dependent manner human plasmatic aminopeptidase leucine5-enkephalin (LEU) metabolism. Half-life peptide degradation was ...
Novos corantes derivados de vinil-calcogenil fenotiazinas: síntese e estudo das propriedades fotofísicas e eletroquímicas
(Universidade Federal de Santa MariaBrasilQuímicaUFSMPrograma de Pós-Graduação em QuímicaCentro de Ciências Naturais e Exatas, 2022-10-21)
This work presents the synthesis and studies of photophysical and electrochemical
behaviour of new phenothiazines derivatives containing the vinyl-chalcogenyl group in
different positions of the heterocyclic. This research ...
NEW SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF PHENOTHIAZINE DERIVATIVES
(Associação Brasileira de Divulgação Científica (ABRADIC), 2014)
On the mechanisms of phenothiazine-induced mitochondrial permeability transition: Thiol oxidation, strict Ca2+ dependence, and cyt c release
(Elsevier B.V., 2010-10-15)
Phenothiazines (PTZ) are drugs widely used in the treatment of schizophrenia. Trifluoperazine, a piperazinic PTZ derivative, has been described as inhibitor of the mitochondrial permeability transition (MPT). We reported ...
The receptor-dependent LQTA-QSAR: application to a set of trypanothione reductase inhibitors
(SpringerDordrechtHolanda, 2012)