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Synchronization of stochastic mean field networks of Hodgkin–Huxley neurons with noisy channels
(Springer Verlag, 2019)
In this work we are interested in a mathematical model of the collective behavior of a fully connected network of finitely many neurons, when their number and when time go to infinity. We assume that every neuron follows ...
The MAP1B case: An old MAP that is new again
(John Wiley, 2014)
The functions of microtubule-associated protein 1B (MAP1B) have historically been linked to the development of the nervous system, based on its very early expression in neurons and glial cells. Moreover, mice in which MAP1B ...
β-catenin aggregation in models of ALS motor neurons: GSK3β inhibition effect and neuronal differentiation
(Academic Press Inc., 2019)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron death. A 20% of familial ALS cases are associated with mutations in the gene coding for superoxide dismutase 1 (SOD1). The ...
The MAP1B case: an old MAP that is new again
(Wiley, 2014)
The functions of microtubuleassociated
protein 1B (MAP1B) have historically been
linked to the development of the nervous system, based
on its very early expression in neurons and glial cells.
Moreover, mice in which ...
Rab-mediated trafficking role in neurite formation
(International Society for Neurochemistry, 2014)
Neuronal cells are characterized by the presence of two
confined domains, which are different in their cellular properties,
biochemical functions and molecular identity. The generation
of asymmetric domains in neurons ...
From birth to death: a role for reactive oxygen species in neuronal development
(Elsevier, 2018-08)
Historically, ROS have been considered toxic molecules, especially when their intracellular concentration reaches high values. However, physiological levels of ROS support crucial cellular processes, acting as second ...
cdk5 modulates β- and δ-catenin/Pin1 interactions in neuronal cells
(2007)
The cdk5/p35 complex has been implicated in a variety of functions related to brain development, including axonal outgrown and neuronal migration. In this study, by co-immunoprecipitation and pull-down experiments, we have ...
Temporal summation in rat prefrontal pyramidal cells. Differential effects of pre- and postsynaptic neurochemical manipulations
(Elsevier, 1983)
The influence of both reserpine-induced depletion of catecolamines and chlorpromazine-induced blockade of dopamine receptors on integrative properties of rats prefrontal pyramidal cells was studied by evocating threshold ...
Exchange Protein Directly Activated by cAMP (EPAC) Regulates Neuronal Polarization through Rap1B
(Soc. Neuroscience, 2015)
Acquisition of neuronal polarity is a complex process involving cellular and molecular events. The second messenger cAMP is involved in axonal specification through activation of protein kinase A. However, an alternative ...
Xiro homeoproteins coordinate cell cycle exit and primary neuron formation by upregulating neuronal-fate repressors and downregulating the cell-cycle inhibitor XGadd45-γ
(2002)
The iroquois (iro) homeobox genes participate in many developmental processes both in vertebrates and invertebrates, among them are
neural plate formation and neural patterning. In this work, we study in detail Xenopus ...