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Effect of GDNF on neuroblast proliferation and photoreceptor survival: additive protection with docosahexaenoic acid
(Association for Research in Vision and Ophthalmology, 2001-11)
Purpose. In a previous study, it was reported that docosahexaenoic acid (DHA) is essential to postpone apoptosis and to promote differentiation of rat retina photoreceptors in vitro. In the current study, the protective ...
Differences in mushroom bodies morphogenesis in workers, queens and drones of Apis mellifera: Neuroblasts proliferation and death
(Pergamon-Elsevier B.V. Ltd, 2010-06-01)
Apis mellifera is an interesting model to neurobiological studies. It has a relatively small brain that commands the complex learning and memory tasks demanded by the social organization. An A. mellifera colony is made up ...
Cell therapy for Parkinson's disease: Functional role of the host immune response on survival and differentiation of dopaminergic neuroblasts
(Elsevier Science, 2016-06)
Parkinson's disease (PD) is a neurodegenerative disorder, whose cardinal pathology is the loss of dopaminergic neurons in the substantia nigra. Current treatments for PD have side effects in the long term and do not halt ...
Cell therapy for Parkinson׳s disease: Functional role of the host immune response on survival and differentiation of dopaminergic neuroblasts
(Elsevier Science, 2015-08)
Parkinson's disease (PD) is a neurodegenerative disorder, whose cardinal pathology is the loss of dopaminergic neurons in the substantia nigra. Current treatments for PD have side effects in the long term and do not halt ...
The serine protease homolog, scarface, is sensitive to nutrient availability and modulates the development of the drosophila blood brain barrier
(Soc. Neuroscience, 2021)
The adaptable transcriptional response to changes in food availability not only ensures animal survival but also lets embryonic development progress. Interestingly, the CNS is preferentially protected from periods of ...
Immunolocalization of myosin Va in the developing nervous system of embryonic chicks
(Springer, 2004-08-01)
Myosins are molecular motors associated with the actin cytoskeleton that participate in the mechanisms of cellular motility. During the development of the nervous system, migration of nerve cells to specific sites, extension ...
Cell cycle regulation in retinal progenitors by glia-derived neurotrophic factor and docosahexaenoic acid
(Association for Research in Vision and Ophthalmology, 2003-05)
PURPOSE. A recent study has shown that glia-derived neurotrophic factor (GDNF) and docosahexaenoic acid (DHA) promote the survival and differentiation of retina photoreceptors. The current study was undertaken to investigate ...
Docosahexaenoic acid promotes photoreceptor differentiation without altering Crx expression
(Association for Research in Vision and Ophthalmology, 2006-07)
PURPOSE: The precise molecular cues required for photoreceptor development are still unknown. Pax6 and Crx are essential during early retinal development and for photoreceptor differentiation, respectively. The lipid ...
The selective glucocorticoid receptor modulator CORT108297 restoresfaulty hippocampal parameters in Wobbler andcorticosterone-treated mice
(Elsevier, 2014-09)
Mutant Wobbler mice are models for human amyotrophic lateral sclerosis (ALS). In addition to spinal cord degeneration, Wobbler mice show high levels of blood corticosterone, hyperactivity of the hypothalamic-pituitary-adrenal ...
Progesterone attenuates several hippocampal abnormalities of the Wobbler mouse
(Wiley, 2013-02-24)
It is now recognised that progesterone plays a protective role for diseases of the central nervous system. In the Wobbler mouse, a model of motoneurone degeneration, progesterone treatment prevents spinal cord neuropathology ...