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Synergism between Terbinafine and a Neo-clerodane Dimer or a Monomer Isolated from Baccharis flabellata against Trichophyton rubrum
(Natural Products, 2019-01)
The new neo-clerodane dimer (DACD) likely formed by a [4+2] photo-cycloaddition between two molecules of ent-15,16-epoxy-19-hydroxy-1,3,13(16),14-clerodatetraen-18-oic acid (DAC), both isolated from Baccharis flabellata ...
Diterpenoids from Baccharis lejía
(1991)
Seven new neoclerodanes have been isolated from aerial parts of Baccharis lejía. Four are dimeric diterpenoids linked via a C-18 malonate ester. Relevant toxicity toward Artemia salina (brine shrimp bioassay) was observed ...
In vivo photoinduced [4 + 2] dimerization of a neo-clerodane diterpene in Baccharis flabellata. ROS and RNS scavenging abilities
(Elsevier Science Sa, 2018-09)
Secondary metabolites play a major role in the adaptation of plants to the environment. Furan neo-clerodane diterpenes are characteristic secondary metabolites in Baccharis flabellata Hook. & Arn. var. flabellata. One of ...
Antinociceptive effect of neo-clerodane diterpenes obtained from Baccharis flabellata
(Elsevier Science, 2018-10)
We report here for the first time antinociceptive effects of extracts from Baccharis flabellata. Two extracts in this analysis, one obtained in summer and the other during winter time. Our results indicate that both extract ...
13- EPI-NEOCLERODANES FROM BACCHARIS MARGINALIS
(2010)
In addition to the known diterpenes, desoxyarticulin and dihydrotucumanoic acid, a new neoclerodane diterpene was isolated from Baccharis marginalis. The structures of the compounds were elucidated by spectroscopic evidence.
Neo-clerodane diterpenoids and other constituents from Baccharis species
(1987)
A new neo-clerodane dilactone, desoxyarticulin, and dihydrotucumanoic acid, together with other known compounds, were isolated from Baccharis pedicellata and Baccharis marginalis. The structures of the new compounds were ...
13- EPI-NEOCLERODANES FROM BACCHARIS MARGINALIS
(Sociedad Chilena de Química, 2010)
Structure of a Neoclerodane Dilactone from Baccharis rhomboidalis
(1990)
1-Hydroxyneoclerodane-3,13-diene- 15,16;-
19,20-diolide, C2oH2605, Mr = 346.42, orthorhombic,
P212121, a = 15-601 (4), b = 15.962 (4), c =
7-093 (2) A, V = 1766.3 A 3, Z= 4, Dx =
1.303 Mg m -3, a(Mo Ka) = 0"71069 A, ...
Neo-clerodane diterpenoid, a new metalloprotease snake venom inhibitor from Baccharis trimera (Asteraceae): anti-proteolytic and anti-hemorrhagic properties
(Elsevier B.V., 2004-12-07)
Many plants are used in traditional medicine as active agents against various effects induced by snakebite. Few attempts have been made however to identify the nature of plain natural products with anti-ophidian properties. ...