Now showing items 1-10 of 144
Microsatellite polymorphism in intron 1 of the bovine myostatin gene
(Journal of applied genetics, 2006)
Myostatin and follistatin expression in skeletal muscles of rats with chronic heart failure
(Wiley-Blackwell Publishing, Inc, 2010-02-01)
P>Skeletal muscle abnormalities can contribute to decreased exercise capacity in heart failure. Although muscle atrophy is a common alteration in heart failure, the mechanisms responsible for muscle mass reduction are not ...
Myostatin: genetic variants, therapy and gene doping
(Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, 2012)
Since its discovery, myostatin (MSTN) has been at the forefront of muscle therapy research because intrinsic mutations or inhibition of this protein, by either pharmacological or genetic means, result in muscle hypertrophy ...
Sequence characterization of coding regions of the myostatin gene (GDF8) from Brazilian Murrah buffaloes (Bubalus bubalis) and comparison with the Bos taurus sequence
(Sociedade Brasileira de Genética, 2006-01-01)
Within about 30 years the Brazilian buffalo (Bubalus bubalis) herd will reach approximately 50 million head as a result of the great adaptive capacity of these animals to tropical climates, together with the good productive ...
Myostatin gene knockdown through lentiviral-mediated delivery of shRNA for in vitro production of transgenic bovine embryos
(CAMBRIDGE UNIV PRESS, 2010)
Myostatin is described as a negative regulator of the skeletal muscle growth. Genetic engineering, in order to produce animals with double the muscle mass and that can transmit the characteristic to future progeny, may be ...
Myocardial myostatin in spontaneously hypertensive rats with heart failure
Background Myostatin has been shown to regulate skeletal and cardiac muscle growth. However, its status on long-term hypertrophied myocardium has not been addressed. The purpose of this study was to evaluate the expression ...
Targeted Nucleotide Exchange in Bovine Myostatin Gene
(Taylor & Francis Inc, 2009-01-01)
The myostatin gene, known as Growth Differentiation Factor 8 (GDF8), located at chromosome 2 (BTA2) in cattle, is specifically expressed during embryo development and in the adult skeletal muscle. Molecular analysis of ...
Expression of MyoD, myogenin, myostatin and Hsp70 transcripts in chicken embryos submitted to mild cold or heat
(Elsevier B.V., 2003-05-01)
The expression of the MyoD, myogenin, myostatin and Hsp70 genes was estimated in chicken embryos submitted to mild cold (36 +/- 0.5degreesC) or heat (44 +/- 0.5degreesC) for 1 h. 2. Marked decreases in MyoD, myogenin and ...