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Interaction of pathogenic fungi with host cells: Molecular and cellular approaches
(Elsevier B.V., 2005-09-01)
This review provides an overview of several molecular and cellular approaches that are likely to supply insights into the host-fungus interaction. Fungi present intra- and/or extracellular host-parasite interfaces, the ...
Pathogenesis II: Fungal responses to host responses: interaction of host cells with fungi
(B I O S Scientific Publishers Ltd, 2000-01-01)
Most of our knowledge concerning the virulence determinants of pathogenic fungi comes from the infected host, mainly from animal models and more recently from in vitro studies with cell cultures. The fungi usually present ...
Histoplasma capsulatum-Induced Cytokine Secretion in Lung Epithelial Cells Is Dependent on Host Integrins, Src-Family Kinase Activation, and Membrane Raft Recruitment
(Frontiers Media Sa, 2016)
Histoplasma capsulatum var. capsulatum is a dimorphic fungus that causes histoplasmosis, a human systemic mycosis with worldwide distribution. In the present work, we demonstrate that H. capsulatum yeasts are able to induce ...
Fungi that Infect Humans
(Amer Soc Microbiology, 2017)
Fungi must meet four criteria to infect humans: growth at human body temperatures, circumvention or penetration of surface barriers, lysis and absorption of tissue, and resistance to immune defenses, including elevated ...
Intermolecular interactions of the malate synthase of Paracoccidioides spp
(2013-05-16)
Background: The fungus Paracoccidioides spp is the agent of paracoccidioidomycosis (PCM), a pulmonary mycosis acquired by the inhalation of fungal propagules. Paracoccidioides malate synthase (PbMLS) is important in the ...
Dual localization of Mdj1 in pathogenic fungi varies with growth temperature
(Informa Healthcare, 2014-02-01)
Paracoccidioides brasiliensis and P. lutzii are temperature-dependent dimorphic fungi that cause paracoccidioidomycosis (PCM). Previously, we characterized the PbMDJ1 gene. This gene encodes P. brasiliensis chaperone Mdj1, ...
Paracoccidioides brasiliensis downmodulates α3 integrin levels in human lung epithelial cells in a TLR2-dependent manner
(Nature, 2020-11-10)
Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis in Latin America and may be caused by the species Paracoccidioides brasiliensis. In the lungs, this fungus interacts with epithelial cells, activating ...
The role of mycorrhization helper bacteria in the establishment and action of ectomycorrhizae associations
(Brazilian Journal of Microbiology, 2017)
Virulence Factors IN Fungi of Systemic Mycoses
(Instituto de Medicina Tropical, 1998-05-01)
Fatores de virulência em fungos de micoses sistêmicaFungos patogênicos causadores de micoses sistêmicas possuem vários fatores que permitem seu crescimento nas condições adversas oferecidas pelo hospedeiro, propiciando o ...
Respiratory epithelial cells: more than just a physical barrier to fungal infections
(MDPI, 2022-05-24)
The respiratory epithelium is highly complex, and its composition varies along the conducting airways and alveoli. In addition to their primary function in maintaining the respiratory barrier and lung homeostasis for gas ...