Buscar
Mostrando ítems 1-10 de 126
Helminths turning on the NLRP3 inflammasome: Pros and cons
(Elsevier, 2020-02)
Helminth infections can activate multimeric protein complexes called inflammasomes. In this forum we summarize the main effects of the NLRP3 inflammasome activation, including control of excessive Th2 response and ...
Intestinal microbiota modulates gluten-induced immunopathology in humanized mice
(American Society of Investigative Pathology, 2015-11)
Celiac disease (CD) is an immune-mediated enteropathy triggered by gluten in genetically susceptible individuals. The recent increase in CD incidence suggests that additional environmental factors, such as intestinal ...
Chronic inflammation as a manifestation of defects in immunoregulatory networks: implications for novel therapies based on microbial products
(Springer, 2009-07)
Based on a unifying theory presented here, it is predicted that the immune defects resulting in chronic inflammation rather than effective immune responses could be rectified by the therapeutic use of agents prepared from ...
Coeliac disease pathogenesis: The uncertainties of a well-known immune mediated disorder
(Frontiers Media, 2020-07-08)
Coeliac disease is a common small bowel enteropathy arising in genetically predisposed individuals and caused by ingestion of gluten in the diet. Great advances have been made in understanding the role of the adaptive ...
The unfolded protein response in alzheimer's diseaseSEMINARS IN IMMUNOPATHOLOGYSEMIN IMMUNOPATHOL
(SPRINGER HEIDELBERG, 2013)