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Chemometric study of the excipients’ influence on polymorphic-behavior: Mefenamic acid as case of study
(Elsevier Science, 2019-06)
The assessment of polymorphism is a problematical issue for regulatory agencies, because variations among crystalline forms of active pharmaceutical ingredient (API) can lead to changes in the efficacy and safety of ...
Estudios de incompatibilidad química del alprazolam con excipientes usados en la preparación de comprimidosChemical incompatibility studies of alprazolam with excipients used in tablet formulations
(Universidad de Antioquia, Facultad de Ciencias Farmacéuticas y AlimentariasGrupo de Estabilidad de Medicamentos, Cosméticos y Alimentos (GEMCA)Medellín, Colombia, 2021)
Effect of silicification on the tableting performance of cellulose II: A novel multifunctional excipient
(Pharmaceutical Society of JapanDiseño y Formulación de Medicamentos Cosméticos y AfinesTokyo, Japón, 2023)
Trifluoroacetic acid as excipient destabilizes melittin causing the selective aggregation of melittin within the centrin-melittin-trifluoroacetic acid complex
(American Crystallographic Association, 2015-05)
Trifluoroacetic acid (TFA) may be the cause of the bottleneck in high resolution structure determination for protein-peptide complexes. Fragment based drug design often involves the use of synthetic peptides which contain ...
Compatibility study of tobramycin and pharmaceutical excipients using differential scanning calorimetry, FTIR, DRX, and HPLC
(Springer, 2018-12)
Differential scanning calorimetry (DSC), isothermal stress testing–Fourier transform infrared spectroscopy (IST–FTIR), isothermal stress testing–high-performance liquid chromatography, and powder X-ray diffraction (PDRX) ...
A New Enhanced Sorbitol: Calcium Diphosphate Composite as A Direct Compression Excipient: A Comparative Study
(IJPPSDiseño y Formulación de Medicamentos Cosméticos y AfinesBhopal, India, 2022)
Preformulation: The use of FTIR in compatibility studies
(South Asian Academic Publications, 2019-07)
Studies of active pharmaceutical ingredient (API) - excipient compatibility represent an important study in the preformulation stage of the development of new dosage forms. The potential physical and chemical interactions ...
Assessment of processing and polymorphic form Effect on the powder and tableting properties of microcrystalline celluloses I and II
(Pharmaceutical Society of JapanDiseño y Formulación de Medicamentos Cosméticos y AfinesTokyo, Japón, 2023)
Chemometrics coupled to vibrational spectroscopy and spectroscopic imaging for the analysis of solid-phase pharmaceutical products: A brief review on non-destructive analytical methods
(Elsevier, 2018-11)
This brief review reports on selected case studies aimed at verifying the authenticity of medicinal products, content uniformity of tablets and polymorphic forms in final products, and monitoring pharmaceutical cocrystallization ...
Prosopis alba exudate gum as novel excipient for fish oil encapsulation in polyelectrolyte bead system
(Elsevier, 2017-06)
In this work, a bottom-up approach based on the study of polyelectrolyte interactions was performed in order to evaluate the effect of Prosopis alba exudate gum as novel excipient for fish oil encapsulation in composed ...