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Formulation and delivery of macromolecules
(Springer New York LLC, 2017)
Delivery of ionizable hydrophilic drugs based on pharmaceutical formulation of ion pairs and ionic liquids
(Elsevier, 2020)
New therapeutics such as antisense oligonucleotides, small interfering RNA and peptide-drug conjugates are taking great relevance in the pharmaceutical industry due to their specificity of action and their improved safety ...
Interchangeability of biological drugs: Considerations about the approval of biogeneric formulations in Chile Intercambiabilidad de medicamentos de origen biológico (biofármacos): Consideraciones acerca de la aprobación de formulaciones biosimilares (biog
(2006)
Once drug patents expire, the health authorities can approve the registry of similar products. They must request to the manufacturer, the bibliographic background of the original product and the analytical results that ...
Depletion study of three formulations of flumequine in edible tissues and drug transfer into chicken feathers
(WILEY-BLACKWELL, 2011-04)
To ensure the delivery of safe animal products to consumers, withdrawal times
(WDT) of drugs must be respected. Drugs administered in therapies can also
reach nonedible tissues (for humans) such as feathers; this transfer ...
Simultaneous determination of dapsone and pyrimethamine by derivative spectrophotometry in pharmaceutical formulations
(AOAC INTERNATIONAL, 2003-03)
A simple and fast method was developed for the simultaneous determination of dapsone and pyrimethamine by first-order digital derivative spectrophotometry. Acetonitrile was used as a solvent to extract the drugs from the ...
A New Methodology to Create Polymeric Nanocarriers Containing Hydrophilic Low Molecular-Weight Drugs: A Green Strategy Providing a Very High Drug Loading
(American Chemical Society, 2019)
To date, a large number of active molecules are hydrophilic and aromatic low molecular-weight drugs (HALMD). Unfortunately, the low capacity of these molecules to interact with excipients and the fast release when a ...
Nanoantioxidant–Based silica particles as flavonoid carrier for drug delivery applications
(MDPI, 2020)
Nanosystems used in pharmaceutical formulations have shown promising results in enhancing the administration of drugs of difficult formulations. In particular, porous silica nanoparticles have demonstrated excellent ...
Simultaneous determination of estradiol and medroxyprogesterone acetate in pharmaceutical formulations by second-derivative spectrophotometry
(AOAC INTERNATIONAL, 2002-07)
This paper reports a simple and fast method for the simultaneous determination of estradiol (ED) and medroxyprogesterone acetate (MP) in pharmaceutical formulations by second-derivative spectrophotometry. Methanol was used ...
Withdrawal time of four pharmaceutical formulations of enrofloxacin in poultry according to different maximum residues limits
(2009)
To ensure delivery of safe animal products to consumers, the withdrawal time
(WDT) of drugs must be respected. Property differences among pharmaceutical
formulations, for the same drugs, can lead to differences in the ...
The effect of chitosan as internal or external coating on the 5-ASA release from calcium alginate microparticles
(2010)
The effect of chitosan as internal or external coating on the mesalamine (5-ASA) release from calcium alginate microparticles (CaAl) was studied, and a delayed release of 5-ASA system intended for colonic drug delivery was ...