Buscar
Mostrando ítems 1-10 de 146
Diversity and population-genetic properties of copy number variations and multicopy genes in cattle
(2016-06-15)
The diversity and population genetics of copy number variation (CNV) in domesticated animals are not well understood. In this study, we analysed 75 genomes of major taurine and indicine cattle breeds (including Angus, ...
Discrepancy variation of dinucleotide microsatellite repeats in eukaryotic genomes
(Sociedad de Biología de Chile, 2009)
Association study between copy number variation and beef fatty acid profile of Nellore cattle
(2018-05-01)
The aim of this study was to analyze the association between the copy number variation regions (CNVRs) and fatty acid profile phenotypes for saturated (SFA), monosaturated (MUFA), polyunsaturated (PUFA), ω6 and ω3 fatty ...
Mitochondrial genotype modulates mtDNA copy number and organismal phenotype in Drosophila
(Elsevier B.V., 2017-05-01)
We evaluated the role of natural mitochondrial DNA (mtDNA) variation on mtDNA copy number, biochemical features and life history traits in Drosophila cybrid strains. We demonstrate the effects of both coding region and ...
MSX2 copy number increase and craniosynostosis: copy number variation detected by array comparative genomic hybridization
(HOSPITAL CLINICAS, UNIV SAO PAULOSAO PAULO, 2012)
Distribution and Functionality of Copy Number Variation across European Cattle Populations
(Frontiers Media Sa, 2017-08-23)
Copy number variation (CNV), which is characterized by large-scale losses or gains of DNA fragments, contributes significantly to genetic and phenotypic variation. Assessing CNV across different European cattle populations ...
Contribution of rare germline copy number variations and common susceptibility loci in Lynch syndrome patients negative for mutations in the mismatch repair genes
(2016-04-15)
In colorectal carcinoma (CRC), 35% of cases are known to have a hereditary component, while a lower proportion (∼5%) can be explained by known genetic factors. In this study, copy number variations (CNVs) were evaluated ...
Copy number variation of individual cattle genomes using next-generation sequencing
(Cold Spring Harbor Lab Press, Publications Dept, 2012-04-01)
Copy number variations (CNVs) affect a wide range of phenotypic traits; however, CNVs in or near segmental duplication regions are often intractable. Using a read depth approach based on next-generation sequencing, we ...
Detection of small copy number variations (CNVs) in autism spectrum disorder (ASD) by custom array comparative genomic hybridization (aCGH)
(Elsevier B.V., 2016-03-01)
Autism spectrum disorder (ASD) has a strong genetic basis and advances in genomic scanning methods have resulted in the identification of the underlying alterations in about 30% of the cases. The overwhelming majority of ...