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Mild cognitive impairment (part 2): Biological markers for diagnosis and prediction of dementia in Alzheimer's disease
(2013-10-14)
To present a critical review of publications reporting on the rationale and clinical implications of the use of biomarkers for the early diagnosis of Alzheimer's disease (AD). Methods: We conducted a systematic search of ...
Mild cognitive impairment (part 2): Biological markers for diagnosis and prediction of dementia in Alzheimer's disease
(2013-10-14)
To present a critical review of publications reporting on the rationale and clinical implications of the use of biomarkers for the early diagnosis of Alzheimer's disease (AD). Methods: We conducted a systematic search of ...
Systematic review: microRNAs as potential biomarkers in mild cognitive impairment diagnosis
(Frontiers Media, 2022)
The rate of progression from Mild Cognitive Impairment (MCI) to Alzheimer's disease (AD) is estimated at > 10% per year, reaching up to 80-90% after 6 years. MCI is considered an indicator of early-stage AD. In this context, ...
Functional magnetic resonance imaging response as an early biomarker of cognitive decline in elderly patients with metabolic syndrome
(Elsevier B.V., 2017-11-01)
Objectives: We assessed whether potential changes in brain activation patterns of elderly individuals with metabolic syndrome (MetS) who were cognitively healthy (without mild cognitive impairment or dementia) were associated ...
Cognitive impairment in remitted late-life depression is not associated with Alzheimer's disease-related CSF biomarkers
(2020-07-01)
Background: Cognitive impairment is a common feature of late-life depression (LLD). Early studies using Alzheimer's disease (AD) biomarkers inferred a biological link between AD pathology and LLD, but recent findings have ...
BDNF as a Biomarker of Cognition in Schizophrenia/Psychosis: An Updated Review
(2021)
Brain Derived Neurotrophic Factor (BDNF) has been linked to cognitive symptoms of schizophrenia, which has been documented in previous reviews by several authors. However, a trend has recently emerged in this field moving ...
Mapping memory binding onto the connectome's temporal dynamics: toward a combined biomarker for Alzheimer's disease
(Frontiers, 2014-04)
En este trabajo proponemos que tras la caída de la hipótesis de cascada amiloide en al enfermedad del Alzheimer (EA), la conectividad cerebral distribuida (que va más allá de regiones clásicamente asociadas a AD, como el ...
Manganese exposure and cognitive deficits: A growing concern for manganese neurotoxicity
(2012)
This symposium comprised five oral presentations dealing with recent findings on Mn-related cognitive and motor changes from epidemiological studies across the life span. The first contribution highlighted the usefulness ...