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Immunization with antigen-pulsed dendritic cells significantly improves the immune response to weak self-antigens
(ELSEVIER GMBH, 2005-09-02)
Dendritic cells (DCs) are the only professional antigen-presenting cells endowed with the ability to stimulate naı¨ve T
cells and initiate a primary immune response. For this reason, DC-based immunization has been shown ...
Octadecyl silica: A solid phase for protein purification by immunoadsorption
(1991)
Immunoaffinity chromatography involves binding of an antigen or antibody to a solid matrix, usually agarose, frequently using the cyanogen bromide method. These methods are laborious, rather expensive, and their use has ...
Recognition of an immunogenetically selected Trypanosoma cruzi antigen by seropositive chagasic human sera
(1997)
If the H-2 congenic mouse strains A.SW (H-2(s)) and A.CA (H-2(f)), are infected with Trypanosoma cruzi, a 45 kDa protein (Tc45), present in cultured epimastigotes and blood trypomastigotes, is recognized only by the A.SW ...
Critical role of HLA-DRb* binding peptides' peripheralflankingresidues in fully-protective malaria vaccine development
(2017)
A vaccine candidate component must fit perfectly into the antigen presenting HLA-DRβ* molecule's groove (or canonical nonapeptide) peptide binding region (PBR) during antigen presentation to the T-cell receptor (TCR), ...
Critical role of HLA-DRβ* binding peptides' peripheral flanking residues in fully-protective malaria vaccine development
(2017)
A vaccine candidate component must fit perfectly into the antigen presenting HLA-DRβ* molecule's groove (or canonical nonapeptide) peptide binding region (PBR) during antigen presentation to the T-cell receptor (TCR), ...
SM-COLSARSPROT: Highly Immunogenic Supramutational Synthetic Peptides Covering the World’s Population
(2022)
Fifty ~20–amino acid (aa)–long peptides were selected from functionally relevant SARS-CoV-2 S, M, and E proteins for trial B-21 and another 53 common ones, plus some new ones derived from the virus’ main genetic variants ...
Encefalitis autoinmune: experiencia de una serie de casos
(Sociedad de Cirugía de Bogotá, Hospital de San José y Fundación Universitaria de Ciencias de la Salud, 2019-02-25)
Toll-like receptor 4 gene polymorphism influences dendritic cell in vitro function and clinical outcomes in vaccinated melanoma patients
(2012)
Toll-like receptor 4 (TLR4) is expressed on dendritic cells (DCs), sensing environmental danger molecules that induce their activation and maturation. Recently, we reported a method for the production of therapeutic DCs ...
Limitaciones para el serodiagnóstico del virus del oeste del Nilo en zonas endémicas con co-circulación de Flavivirus en el Caribe colombiano.
(2013-10-29)
Introducción: Esta es la primera aproximación sero-epidemiológica que se hace en Colombia sobre el virus del Oeste del Nilo
(VON).
Objetivo: El propósito de este estudio fue el de establecer la presencia de anticuerpos ...
Surface Immunogenic Protein of Streptococcus Group B is an Agonist of Toll-Like Receptors 2 and 4 and a Potential Immune Adjuvant
(MDPI, 2020)
Vaccine-induced protection against pathogens, especially subunit-based vaccines, are related to antigen properties but mainly in their ability to stimulate the immune system by the use of an adjuvant. Modern vaccines are ...