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Morphometric analysis of the phrenic nerve in male and female Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR)
(Associação Brasileira de Divulgação Científica, 2011)
Ventilatory differences between rat strains and genders have been described but the morphology of the phrenic nerve has not been investigated in spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) rats. A ...
Transcriptome analysis of nicotine-exposed cells from the brainstem of neonate spontaneously hypertensive and Wistar Kyoto rats
(NATURE PUBLISHING GROUP, 2010)
In this study, the effects of nicotine on global gene expression of cultured cells from the brainstem of spontaneously hypertensive rat (SHR) and normotensive Wistar Kyoto (WKY) rats were evaluated using whole-genome ...
Intra-strain variations of baroreflex sensitivity in young Wistar-Kyoto rats
(CANADIAN SOC CLINICAL INVESTIGATION, 2009)
Purpose: To compare baroreflex sensitivity among conscious rats of the same strain. Methods: Male WKY rats (eight weeks old) were studied. Cannulas were inserted into the abdominal aortic artery through the right femoral ...
Sural nerve involvement in experimental hypertension: morphology and morphometry in male and female normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR)
(BIOMED CENTRAL LTDLONDON, 2012)
Background: The sural nerve has been widely investigated in experimental models of neuropathies but information about its involvement in hypertension was not yet explored. The aim of the present study was to compare the ...
Gene Expression Profiling of Cultured Cells From Brainstem of Newborn Spontaneously Hypertensive and Wistar Kyoto Rats
(SPRINGER/PLENUM PUBLISHERS, 2009)
The spontaneously hypertensive rat (SHR) is a good model to study several diseases such as the attention-deficit hyperactivity disorder, cardiopulmonary impairment, nephropathy, as well as hypertension, which is a multifactor ...
Lesions of the commissural nucleus of the solitary tract reduce arterial pressure in spontaneously hypertensive rats
(Lippincott Williams & Wilkins, 2001-09-01)
It has been suggested that increased sympathetic activity and arterial chemoreceptors are important for the high blood pressure in spontaneously hypertensive rats (SHR). Electrolytic lesions of the commissural nucleus of ...
Expression and localization of NK1R, substance P and CGRP are altered in dorsal root ganglia neurons of spontaneously hypertensive rats (SHR)
(Elsevier Science BvAmsterdamHolanda, 2005)
Adenosine receptor type 2a is differently modulated by nicotine in dorsal brainstem cells of Wistar Kyoto and spontaneously hypertensive rats
(SPRINGER WIEN, 2010)
Hypertension can result from neuronal network imbalance in areas of central nervous system that control blood pressure, such as the nucleus tractus solitarius (NTS). There are several neurotransmitters and neuromodulatory ...
Genotoxic studies in hypertensive and normotensive rats treated with amiodarone
(ELSEVIER SCIENCE BV, 2008)
Amiodarone, a benzofuran derivative. is a very effective antiarrhythmic medication, but has potential to cause side effects. Although its cytotoxicity potential is very well-known, there are few reports about its genotoxicity ...
Matrix metalloproteinases cleave the beta(2)-adrenergic receptor in spontaneously hypertensive rats
(AMER PHYSIOLOGICAL SOC, 2010)
Rodrigues SF, Tran ED, Fortes ZB, Schmid-Schonbein GW. Matrix metalloproteinases cleave the beta(2)-adrenergic receptor in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 299: H25-H35, 2010. First published ...