Search
Now showing items 1-10 of 10
Relationship between head and neck cancer therapy and some genetic endpoints
(Baishideng Publishing Group Inc, 2014-05-10)
Head and neck cancer (HNC) is the sixth most common human malignancy worldwide. The main forms of treatment for HNC are surgery, radiotherapy (RT) and chemotherapy (CT). However, the choice of therapy depends on the tumor ...
Use of Copaifera multijuga for acute corneal repair after chemical injury: A clinical, histopathological and toxicogenetic study
(Elsevier B.V., 2017-12-01)
Copaiba oil is widely used in medicine, but there are no reports regarding its application in ophthalmology. Therefore, the objective of this study was to evaluate the clinical, histopathological and toxicogenetic effects ...
Toxicogenetic monitoring in urban cities exposed to different airborne contaminants
(2013-04-01)
Microparticles found in the air may be associated with organic matter that contains several compounds, such as Polycyclic Aromatic Hydrocarbons (PAHs) and nitro-PAHs, and may pose a significant risk to human health, possibly ...
Haplotypes of vitamin D receptor modulate the circulating levels of lead in exposed subjects
(SPRINGER, 2008)
Genetic factors influence whole blood lead (Pb-B) concentrations in lead exposed subjects. This study aimed at examining the combined effects (haplotype analysis) of three polymorphisms (BsmI, ApaI and FokI) in vitamin D ...
Toxicogenetic effects of low concentrations of the pesticides imidacloprid and sulfentrazone individually and in combination in in vitro tests with HepG2 cells and Salmonella typhimurium
(Elsevier B. V., 2015)
The insecticide imidacloprid and the herbicide sulfentrazone are two different classes of pesticides that are used for pest control in sugarcane agriculture. To evaluate the genotoxic potential of low concentrations of ...
Black bean (Phaseolus vulgaris L.) as a protective agent against DNA damage in mice
(Elsevier B.V., 2003-12-01)
This study was designed to evaluate the toxicogenetic or protective effect of cooked and dehydrated black beans (Phaseolus vulgaris L.) in bone marrow and peripheral blood cells of exposed mice. The frequency of micronuclei ...
Mimosa (Mimosa caesalpiniifolia) prevents oxidative DNA damage induced by cadmium exposure in Wistar rats
(Informa Healthcare, 2014-12-01)
The Mimosa (Mimosa caesalpiniifolia) is a plant native from South America; it is used in the traditional medicine systems for treating bacterial, fungal, parasitic and inflammatory conditions. The aim of this study was to ...
Cytotoxic and toxicogenomic effects of silibinin in bladder cancer cells with different TP53 status
(Indian Acad Sciences, 2017-03-01)
Silibinin is a natural phenol found in the seeds of the milk thistle plant. Recent data have shown its effectiveness for preventing/treating bladder tumours. Therefore, in this study we investigated the cytotoxic and ...
Toxicological effects of the waste of the sugarcane industry, used as agricultural fertilizer, on the test system Allium cepa
(2017-01-01)
Sugarcane is cultivated in tropical countries for sugar and ethanol production. In Brazil, this culture is among the most profitable with a production of 658.7 million tons/harvest. Sugarcane filter cake (SCFC) is a waste ...