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Interaction between substance P and TRH in the control of prolactin release
(BioScientifica, 2000-02)
Substance P (SP) may participate as a paracrine and/or autocrine factor in the regulation of anterior pituitary function. This project studied the effect of TRH on SP content and release from anterior pituitary and the ...
Cardiovascular and body weight regulation changes in transgenic mice overexpressing thyrotropin-releasing hormone (TRH)
(Servicio Publicaciones Universidad Navarra, 2020-09-11)
Thyrotropin-releasing hormone (TRH) plays several roles as a hormone/neuropeptide. Diencephalic TRH (dTRH) participates in the regulation of blood pressure in diverse animal models, independently of the thyroid status. The ...
Angiotensin II requires an intact cardiac Thyrotropin-Releasing Hormone (TRH) system to Induce cardiac hypertrophy in mouse
(Academic Press Ltd - Elsevier Science Ltd, 2018-11)
Cardiac tyhrotropin-releasing hormone (TRH) is overexpressed in the hypertrophied left ventricle (LV) of spontaneously hypertensive rats (SHR) and its inhibition prevents both hypertrophy and fibrosis. In a normal heart, ...
Association between diencephalic thyroliberin and arterial blood pressure in agouti-yellow and ob/ob mice may be mediated by leptin
(W B Saunders Co-Elsevier Inc, 2007-10)
Leptin, a hormone secreted by the adipose tissue, stimulates anorexigenic peptides and also inhibits orexigenic peptides in hypothalamic arcuate nuclei-located neurons. It also counteracts the starvation-induced suppression ...
Short-term doxorubicin cardiotoxic effects: involvement of cardiac Thyrotropin Releasing Hormone system
(Pergamon-Elsevier Science Ltd, 2020-08)
Doxorubicin is an antineoplastic in the anthracycline class widely used for the treatment of several solid tumors and blood cancers. Cardiotoxicity is the major dose-limiting adverse effect of the drug. Chronic and accumulated ...
Knocking down of diencephalic thyrotropin-releasing hormone precursor gene normalizes obesity-induced hypertension in the rat
(American Physiological Society, 2007-05-01)
We recently showed that diencephalic TRH may mediate the central leptin-induced pressor effect. Here, to study the role of TRH in obesity-induced hypertension (OIH), we used a model of OIH produced by a high-fat diet (HFD, ...
Short-term cold exposure activates TRH neurons exclusively in the hypothalamic paraventricular nucleus and raphe pallidus
(Elsevier Ireland, 2012-06)
The neuropeptide thyrotropin releasing hormone (TRH) is necessary for adequate cold-induced thermogenesis. TRH increases body temperature via both neuroendocrine and autonomic mechanisms. TRH neurons of the hypothalamic ...
Thyrotropin-releasing hormone in cardiovascular pathophysiology
(Elsevier Science, 2005-12)
Thyrotropin (TSH)-releasing hormone (TRH) also known as thyroliberin was the first of a number of peptides exerting several roles as a hormone and as a neuropeptide. Its ubiquitous distribution in the hypothalamus and in ...
Tanycytes and the control of thyrotropin-releasing hormone flux into portal capillaries
(Frontiers Research Foundation, 2019)
Análisis costo-efectividad de la terapia de reemplazo hormonal (TRH) frente a isoflavonas en osteoporosis posmenopáusica
(Colegio Médico del Perú, 2009)