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Functional Analysis of the TCR Binding Domain of Toxic Shock Syndrome Toxin-1 Predicts Further Diversity in MHC Class II/Superantigen/TCR Ternary Complexes
(American Association of Immunologists, 2003-07)
Superantigens (SAGs) aberrantly alter immune system function through simultaneous interaction with lateral surfaces of MHC class II molecules on APCs and with particular variable regions of the TCR beta-chain (Vbeta). To ...
Constant tcr triggering suggests that the tcr expressed on intestinal intraepithelial gamma delta t cells is functional in vivo
(WILEY-V C H VERLAG GMBH, 2010)
Procedimento para a defesa de TCR na residência
(Fiocruz/Farmanguinhos, 2022)
TCRpMHCmodels: Structural modelling of TCR-pMHC class I complexes
(Nature Publishing Group, 2019-10)
The interaction between the class I major histocompatibility complex (MHC), the peptide presented by the MHC and the T-cell receptor (TCR) is a key determinant of the cellular immune response. Here, we present TCRpMHCmodels, ...
The half life of TCR/pMHC interaction can modulate T cell activation in response to
(2007)
T cell activation results from T cell receptor (TCR) engagement by cognate peptide-MHC (pMHC) complexes on the surface of antigen presenting cells (APCs). We have previously shown that the half-life of the TCR/pMHC interaction ...
Structures of Two Streptococcal Superantigens Bound to TCR β Chains Reveal Diversity in the Architecture of T Cell Signaling Complexes
(Cell Press, 2002-05)
Superantigens (SAGs) crosslink MHC class II and TCR molecules, resulting in an overstimulation of T cells associated with human disease. SAGs interact with several different surfaces on MHC molecules, necessitating the ...
ON STRESS-RELAXATION
(Akademie Verlag GmbhBerlinAlemanha, 1982)