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Non-visual photopigments effects of constant light-emitting diode light exposure on the inner retina of Wistar rats
(Frontiers Media S.A., 2017-08)
The retina is part of the central nervous system specially adapted to capture light photons and transmit this information to the brain through photosensitive retinal cells involved in visual and non-visual activities. ...
Degeneración retinal, Retinitis Pigmentosa: generalidades, mutaciones en el mecanismo de fototransducción y modelo de investigación
(Universidad Nacional de Córdoba. Facultad de Ciencias Químicas, 2013-08)
La degeneración retinal (DR) es un proceso patológico que provoca muerte de célulasretinales, pérdida de estructura del tejido y finalmente ceguera. Retinitis pigmentosa (RP) comprende un grupo de distrofias retinales que ...
Photoreceptor damage induced by low-intensity light: model of retinal degeneration in mammals
(Molecular Vision, 2013-07)
Purpose: Retinal degeneration caused by a defect in the phototransduction cascade leads to the apoptosis of photoreceptor cells, although the precise molecular mechanism is still unknown. In addition, constant low light ...
Possible mechanisms of retinal function recovery with the use of cell therapy with bone marrow-derived stem cells
(Conselho Brasileiro de Oftalmologia, 2010)
Bone marrow has been proposed as a potential source of stem cells for regenerative medicine. In the eye, degeneration of neural cells in the retina is a hallmark of such widespread ocular diseases as age-related macular ...
Superior cervical gangliectomy induces non-exudative age-related macular degeneration in mice
(Company of Biologists, 2018)
Abstract: Non-exudative age-related macular degeneration, a prevalent cause of blindness, is a progressive and degenerative disease characterized by alterations in Bruch's membrane, retinal pigment epithelium, and ...
Specific roles for Group V secretory PLA2 in retinal iron-induced oxidative stress. Implications for age-related macular degeneration
(Elsevier, 2013-06)
Iron accumulation and oxidative stress are hallmarks of retinas from patients with age-related macular degeneration (AMD). We have previously demonstrated that iron-overloaded retinas are a good in vitro model for the study ...
Degenerate Two-Photon Absorption in All-Trans Retinal: Nonlinear Spectrum and Theoretical Calculations
(AMER CHEMICAL SOC, 2010)
In this work we investigate the degenerate two-photon absorption spectrum of all-trans retinal ill ethanol employing the Z-scan technique with femtosecond pulses, The two-photon absorption (2PA) spectrum presents a monotonous ...
Diet-induced obesity impairs AKT signalling in the retina and causes retinal degeneration
(2013-01-01)
Retinopathy, a common complication of diabetes, is characterized by an unbalanced production of nitric oxide (NO), a process regulated by nitric oxide synthase (NOS). We hypothesized that retinopathy might stem from changes ...
Oxidative stress damage circumscribed to the central temporal retinal pigment epithelium in early experimental non-exudative age-related macular degeneration
(Elsevier, 2019)
Abstract: Non-exudative age-related macular degeneration (NE-AMD) represents the leading cause of blindness in the elderly. The macular retinal pigment epithelium (RPE) lies in a high oxidative environment because its high ...
p75NTR antagonists attenuate photoreceptor cell loss in murine models of retinitis pigmentosa
(Nature Publishing Group, 2017-07)
ProNGF signaling through p75NTR has been associated with neurodegenerative disorders. Retinitis pigmentosa (RP) comprises a group of inherited retinal dystrophies that causes progressive photoreceptor cell degeneration and ...