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Mostrando ítems 1-10 de 19
Ovarian angiogenesis in polycystic ovary syndrome
(BioScientifica, 2018-05)
Polycystic ovary syndrome (PCOS) is the most prevalent endocrine pathology among women in reproductive age. Its main symptoms are oligo or amenorrhea, hyperandrogenism and the presence of ovarian cysts. It is also associated ...
The role of ACTH in the pathogenesis of Polycystic Ovarian Syndrome in the rat: hormonal profiles and ovarian morphology.
(Acad Sciences Czech Republic, 2007-12)
Numerous hypotheses have been proposed about the pathogenia of the polycystic ovarian syndrome (PCOS). However, hormonal control of the persistent follicle has not been established. The objective of the present study was ...
Disruption in the expression and immunolocalisation of steroid receptors and steroidogenic enzymes in letrozole-induced polycystic ovaries in rat
(Csiro Publishing, 2009-12)
The objective of the present study was to characterise the expression and tissue distribution of steroid receptors (oestrogen receptor- and (ER, ER), androgen receptor (AR) and progesterone receptor (PR)) and steroidogenic ...
Comparing the role of anti-Müllerian hormone as a marker of FSH action in male and female fertility
(Taylor & Francis, 2019-03)
Introduction: Originally limited to the assessment of patients with congenital disorders of sexdevelopment, anti-Müllerian hormone (AMH) measurement has more recently been extended toseveral conditions affecting the ...
Angiopoietins/TIE2 system and VEGF are involved in ovarian function in a DHEA rat model of Polycystic Ovary Syndrome
(Endocrine Society, 2012-07)
Polycystic ovary syndrome (PCOS) is the most common endocrinological pathology among women of reproductive age. It is characterized by anovulation, oligo- or amenorrhea, hyperandrogenism, obesity, and insulin resistance. ...
Macrophage secretions modulate the steroidogenesis of polycystic ovary in rats: Effect of testosterone on macrophage pro-inflammatory cytokines
(Pergamon-Elsevier Science Ltd, 2012-05)
Aims: The macrophage secretions' effect on ovarian steroidogenesis is investigated in a polycystic ovary syndrome rat model (PCO rat). The influence of testosterone environment on the expression of macrophage pro-inflammatory ...
Role of the N, N′-dimethylbiguanide metformin in the treatment of female prepuberal BALB/c mice hyperandrogenized with dehydroepiandrosterone
(BioScientifica, 2006-03)
The present study investigated the role of the N, N{ 0 }-dimethylbiguanide metformin (50 mg/100 g body weight in 0.05 ml water, given orally with a canulla) in the prevention of endocrine and immune disorders provoked by ...
Androgen receptor and uterine histoarchitecture in a PCOS rat model
(Elsevier Ireland, 2020-08)
Polycysticovary syndrome (PCOS) is associated with hyperandrogenemia and uterine abnormalities.Our aim was to investigate the uterine effects of PCOS that are mediated throughthe androgen receptor (AR). After weaning, ...
Fetal programming by androgen excess in rats affects ovarian fuel sensors and steroidogenesis
(Cambridge University Press, 2019-02)
Fetal programming by androgen excess is hypothesized as one of the main factors contributing to the development of polycystic ovary syndrome (PCOS). PCOS is more than a reproductive disorder, as women with PCOS also show ...