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Proline-rich extensin-like receptor kinases PERK5 and PERK12 are involved in pollen tube growth
(John Wiley & Sons Ltd, 2021-10)
Proline-rich extensin-like receptor kinases (PERKs) belong to the hydroxyproline-rich glycoprotein (HRGP) superfamily known to be involved in many plant developmental processes. Here, we characterized two pollen-expressed ...
Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease
(Academic Press Inc., 2018)
© 2018 Elsevier Inc. Parkinson's disease (PD) is the second most common neurodegenerative disorder, leading to the progressive decline of motor control due to the loss of dopaminergic neurons in the substantia nigra pars ...
Modulation of the Akt pathway reveals a novel link with PERK/eIF2alpha, which is relevant during hypoxia
(Public Library Science, 2013-07-29)
The unfolded protein response (UPR) and the Akt signaling pathway share several regulatory functions and have the capacity to determine cell outcome under specific conditions. However, both pathways have largely been studied ...
Perk
(2021)
Perk
(2021)
Perk
(2021)
Perk
(2021)
Perk
(2021)
Perk
(2021)
Perk
(2021)