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ESR, electrochemical and ORAC studies of nitro compounds with potential antiprotozoal activity
(2010)
Cyclic Voltammetry (CV) and electron spin resonance (ESR) techniques were used in the investigation of several potentially antiprotozoal nitro derivatives of dihydroquinoxaline and indazole. A self-protonation process ...
Recent developments in the electrochemistry of some nitro compounds of biological significance
(BENTHAM SCIENCE PUBL, 2005-04)
The redox chemistry of different nitro compounds of biological significance is focused to understand how the reduction of the nitro group can play an active role in several aspects as: electroanalytical determinations, ...
Electrocatalytic determination of NADH by means of electrodes modified with MWCNTs and nitroaromatic compounds
(Elsevier, 2020)
In this work, we have both synthesized and studied 4-phenylbutyl-3,5-dinitrobenzoate (3,5-DNBPh) as a potential precursor of an electrocatalytic mediator for the oxidation of NADH, with the di-nitro compound immobilized ...
Cyclic voltammetric studies on nitro radical anion formation from megazol and some related nitroimidazole derivatives
(ELSEVIER SCIENCE, 2001-09-21)
Megazol (2-amino-5-(1-methyl-5-nitro-2-imdazolyl)-1,3,4-thiadiazol, CAS 19622-55-0) and related nitroimidazole compounds are being tested as antichagasic drugs. Little is known on the mode of action of megazol. However, ...
Liver microsomal biotransformation of nitro-aryl drugs: Mechanism for potential oxidative stress induction
(JOHN WILEY & SONS LTD, 2004-11)
Toxic effects of several nitro-aryl drugs are attributed to the nitro-reduction that may be suffered in vivo, a reaction that may be catalysed by different reductases. One of these enzymes is NADPH-cytochrome P450 reductase, ...
Cyclic voltammetric determination of free radical species from nitroimidazopyran: a new antituberculosis agent
(ELSEVIER SCIENCE, 2004-01-15)
PA-824 (2-nitro-6-(4-trifluoromethoxy-benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine) is being tested as antituberculosis drug. Little is known on the action mechanism of PA-824; however the reduction of the nitro ...
Voltammetric study of 7-nitro-1,4-benzodiazepin-2-ones and their acid hydrolysis products, 2-amino-5-nitrobenzophenones
(1990)
The electrochemical reduction of 7-nitro-1,4-benzodiazepin-2-ones and of their acid hydrolysis products, 2-amino-5-nitrobenzophenones, was studied by polarography and cyclic voltammetry in a solvent - buffer system containing ...
Voltammetric studies of aromatic nitro compounds: pH-dependence on decay of the nitro radical anion in mixed media
(ELSEVIER SCIENCE, 2000-12-01)
In this report we have chosen ethyl-m-nitrobenzoate (EMNB) as a prototype of a nitroaromatic compound in order to carry out a detailed cyclic voltammetric study focused on the coupled chemical reaction of the generated ...
Nitro radical anions from megazol and related nitroimidazoles in aprotic media. A father-son type reaction triggered by an acidic proton
(PERGAMON-ELSEVIER SCIENCE, 2002-09-25)
We have studied the electrochemical reduction of some nitroimidazoles such as megazol(2-amino-5-(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazol, CAS 19622-55-0) and two related derivatives in aprotic media (100% DMF, 0.1 ...
Reduction of different nitro-compounds on electroenzymatic system: Cytochrome c reductase-NAD(P)H modified carbon paste electrode
(WILEY-V C H VERLAG GMBH, 1999-11)
A flavoenzyme cytochrome c reductase NAD(P)H mixture has been used to modify a carbon paste electrode. The modified electrode was characterized by cyclic voltammetry varying the scan rate and temperature. Cathodic and ...