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Inhibition of the hemorrhagic activity of Bothrops asper venom by a novel neutralizing mixture
(1997-06)
This study screened 25 sera, 19 synthetic products and five antivenoms obtained after immunization for their ability to neutralize the hemorrhagic activity of venom from the snake Bothrops asper. Among the sera screened, ...
A time- and cost-effective strategy to sequence mammalian Y Chromosomes: an application to the de novo assembly of gorilla Y
(2016-02)
The mammalian Y Chromosome sequence, critical for studying male fertility and dispersal, is enriched in repeats and palindromes, and thus, is the most difficult component of the genome to assemble. Previously, expensive ...
Magnitude and impact of diarrhoeal disease
(1988-12)
Diarrhoea seems to be a minor problem in humans and other mammals
living in small, isolated tribes or groups. Under such conditions there is
limited, if any, introduction of pathogenic agents and, if agents are ...
Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score
(2015-09-15)
For more than 100 years, antivenoms have been produced by traditional methods of immunization of large mammals with mixtures of snake venoms (World Health Organization, 2010 and Gutiérrez et al., 2011). With the introduction ...
All-offspring natal philopatry in a Neotropical bat
(2011-11)
Natal dispersal is a strategy employed by individuals to avoid reproducing with close relatives. In most
bats, incestuous matings are prevented by the departure of one sex; thus, all-offspring philopatry has
rarely been ...
Brucella abortus Strain 2308 Wisconsin Genome: Importance of the Definition of Reference Strains
(2016-09-29)
Brucellosis is a bacterial infectious disease affecting a wide range of mammals and a
neglected zoonosis caused by species of the genetically homogenous genus Brucella.
As in most studies on bacterial diseases, research ...
High-density peptide microarray exploration of the antibody response in a rabbit immunized with a neurotoxic venom fraction
(2017-11)
Polyvalent snakebite antivenoms derive their therapeutic success from the ability of their antibodies to
neutralize venom toxins across multiple snake species. This ability results from a production process
involving ...
Toxicovenomics and antivenom profiling of the Eastern green mamba snake (Dendroaspis angusticeps).
(2016-03-16)
A toxicovenomic study was performed on the venom of the green mamba, Dendroaspis angusticeps. Forty-two different proteins were identified in the venom of D. angusticeps, in addition to the nucleoside adenosine. The most ...
Snake Venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus Complex Points to Neurotoxicity as an Adaptive Paedomorphic Trend along Crotalus Dispersal in South America
(2010)
We report a comparative venomic and antivenomic characterization of the venoms of newborn and adult specimens of the Central American rattlesnake, Crotalus simus, and of the subspecies cumanensis, durissus, ruruima, and ...
Virología de los rotavirus y epidemiología de la diarrea por rotavirus
(1985)
Rotaviruses are a leading cause of morbid- feeding infants and children of tender age
ity and mortality from diarrhea among breast- everywhere in the world, and particularly in microorganisms
replicate in the villose ...