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Losartan reverses impaired osseointegration in spontaneously hypertensive rats
(Wiley-Blackwell, 2018-11-01)
Objective Hypertension is not only associated with cardiovascular diseases but also with alterations in bone quality. Hypertension therefore might be a risk factor for osseointegration. Preclinical studies suggest that ...
IN VITRO EVIDENCES FOR SIMVASTATIN AND LOSARTAN POTASSIUM INTERACTION AND ITS IN VIVO IMPLICATIONS
(Sociedad Chilena de Química, 2009)
Losartan improves alveolar bone dynamics in normotensive rats but not in hypertensive rats
(2019-01-01)
Hypertension is one of the main causes of premature death in the world; also, it is associated with several bone alterations. Preclinical studies have demonstrated delayed alveolar bone healing in hypertensive rats. However, ...
A simple and precise conductometric method for the determination of losartan in pharmaceutical products
(VERSITAWARSAW, 2012)
Losartan is an antihypertensive agent that lost its patent protection in 2010, and, consequently, it has been available in generic form. The latter motivated the search for a rapid and precise alternative method. Here, a ...
Losartan improves alveolar bone dynamics in normotensive rats but not in hypertensive rats
(Faculdade De Odontologia De Bauru - USP, 2019-10-07)
Hypertension is one of the main causes of premature death in the world; also, it is associated with several bone alterations. Preclinical studies have demonstrated delayed alveolar bone healing in hypertensive rats. However, ...
The AT1 receptor antagonist losartan does not affect depressive-like state and memory impairment evoked by chronic stressors in rats
(2019-01-01)
The present study investigated the effect of the treatment with the angiotensin II type 1 receptor (AT1) antagonist losartan in the depressive-like state and memory impairment evoked by exposure to either homotypic (i.e., ...
Losartan, a selective inhibitor of subtype AT1 receptors for angiotensin II, inhibits neutrophil recruitment in the lung triggered by fMLP
(Federation of American Societies for Experimental Biology, 2000-11)
We have shown that losartan, a selective inhibitor of AT1 receptors for angiotensin II (AII), inhibits the binding of [3H]fMLP to neutrophil receptors (FPR). Here, we analyze, in Wistar rats, the effect of losartan on ...
Losartan (DUP-753) blocks the natriuretic, kaliuretic and antidiuretic effect of intracerebroventricular injection of carbachol in water-loaded rats
(Associação Brasileira de Divulgação Científica (ABRADIC), 1996-04-01)
We determined the effect of intracerebroventricular (icv) administration of losartan, an angiotensin II (ANG II) subtype 1 receptor (AT1) antagonist, on icv carbachol-induced natriuresis, kaliuresis and antidiuresis in ...
Losartan (DUR-753) blocks the natriuretic, kaliuretic and antidiuretic effect of intracerebroventricular injection of carbachol in water-loaded rats
(1996-12-01)
We determined the effect of intracerebroventricular (icv) administration of losartan, an angiotensin II (ANG II) subtype 1 receptor (AT1) antagonist, on icv carbachol-induced natriuresis, kaliuresis and antidiuresis in ...