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Type B Insulin Resistance in Peru
(Elsevier, 2016)
Type B insulin resistance (IR) is a rare autoimmune disease characterized by the presence of insulin receptor autoantibodies, resulting in a marked IR inducing hyperglycemia. Our first case is a 42-year-old female with a ...
Islet adaptive changes to fructose-induced insulin resistance: β-cell mass, glucokinase, glucose metabolism, and insulin secretion
(BioScientifica, 2009-02)
β-Cell mass, hexokinase/glucokinase (HK/GK) activity, glucose metabolism and insulin secretion were studied in the islets of rats with fructose-induced insulin resistance (IR). Normal male Wistar rats were fed a standard ...
Changes in islet plasma membrane calcium-ATPase activity and isoform expression induced by insulin resistance
(Elsevier Science Inc, 2009-10)
We studied the effect of insulin resistance (IR) induced by administration of a fructose-rich diet (FRD) to normal Wistar rats for 21 days, upon islet plasma membrane calcium ATPases (PMCAs) and insulin secretion. FRD rats ...
Reduced insulin sensitivity as a marker for acute mountain sickness?
(Mary Ann Liebert, 2013)
The diabetogenic side effects of dexamethasone should therefore be considered for AMS treatment. To examine whether reduced insulin sensitivity is predictive of AMS and how it is affected by dexamethasone at high altitude, ...
Association between Insulin Resistance and Breast Carcinoma: A Systematic Review and Meta-Analysis
(Public Library of Science (PLoS), 2014-06-09)
Objective: This study was undertaken to evaluate the association between components defining insulin resistance and breast cancer in women. Study Design: We conducted a systematic review of four databases (PubMed-Medline, ...
Obesity-related insulin resistance in adolescents: a systematic review and meta-analysis of observational studies
(Taylor and Francis Ltd, 2017-01-19)
Insulin resistance is common among obese adolescents; however, the extent of this problem is not clear. We conducted a systematic review of PubMed-Medline, CINAHL, The Web of Science, EMBASE and Scopus for observational ...
(-)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress
(Elsevier Science Inc, 2014-07)
We investigated the capacity of dietary (-)-epicatechin (EC) to mitigate insulin resistance through the modulation of redox-regulated mechanisms in a rat model of metabolic syndrome (MetS). Adolescent rats were fed a regular ...
Insulin resistance and endometrial cancer risk: A systematic review and meta-analysis
(Elsevier B.V., 2015-12)
Abstract Aim: It has been suggested that chronic hyperinsulinemia from insulin resistance is involved in the etiology of endometrial cancer (EC). We performed a systematic review and meta-analysis to assess whether insulin ...
Insulin resistance by homeostasis model assessment in HIV-infected patients on highly active antiretroviral therapy: cross-sectional study
(Springer, 2015)
BACKGROUND: The highly active antiretroviral therapy (HAART) has altered the course of HIV infection, transforming it from a fatal illness to a chronic condition, reducing morbidity and mortality. However, this therapy has ...
(-)-Epicatechin improves insulin sensitivity in high fat diet-fed mice
(Elsevier Science Inc, 2016-06)
Obesity constitutes a major public health concern, being frequently associated with type 2 diabetes (T2D). Evidence from studies in humans and experimental animals suggest that consumption of the flavan-3-ol (-)-epicatechin ...