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Chronic sodium fluoride intake promotes changes in insulin signaling and inflammatory pathways in the skeletal muscle of rats
(Int Soc Fluoride Research, 2021-10-01)
This study aimed to investigate the final step of insulin signaling and the relationship between the inflammatory pathway and insulin signal attenuation in the gastrocnemius muscle (GM) of rats chronically treated with ...
MILD CHRONIC NaF INTAKE PROMOTES INSULIN RESISTANCE AND INCREASE IN INFLAMMATORY SIGNALING IN THE WHITE ADIPOSE TISSUE OF RATS
(Int Soc Fluoride Research, 2019-01-01)
Excessive fluoride intake is associated with systemic metabolic alterations similar to those observed in type 2 diabetes such as decreased insulin secretion, impaired glycemic control, and insulin resistance. However, the ...
Requirement of mitogen-activated protein kinases and I kappa B phosphorylation for induction of proinflammatory cytokines synthesis by macrophages indicates functional similarity of receptors triggered by glycosylphosphatidylinositol anchors from parasitic protozoa and bacterial lipopolysaccharide
(Amer Assoc Immunologists, 2001-03-01)
present study, we evaluated the ability of GPI-anchored mucin-like glycoproteins purified from Trypanosoma cruzi trypomastigotes (tGPI-mucin) to trigger phosphorylation of different mitogen-activated protein kinases (MAPKs) ...
Iron overload-modulated nuclear factor kappa-B activation in human endometrial stromal cells as a mechanism postulated in endometriosis pathogenesis
(Elsevier, 2015)
Objective: To evaluate the effect of iron overload on nuclear factor kappa-B (NF-kappa B) activation in human endometrial stromal cells (ESCs).
Design: Experimental study.
Setting: University hospital research ...
Metformin Attenuates the Exacerbation of the Allergic Eosinophilic Inflammation in High Fat-Diet-Induced Obesity in Mice
(Public Library ScienceSan FranciscoEUA, 2013)
Quercetin decreases inflammatory response and increases insulin action in skeletal muscle of ob/ob mice and in L6 myotubes
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
Quercetin is a potent anti-inflammatory flavonoid, but its capacity to modulate insulin sensitivity in obese insulin resistant conditions is unknown. This study investigated the effect of quercetin treatment upon insulin ...
Reversion of Steatosis by SREBP-1c Antisense Oligonucleotide did not Improve Hepatic Insulin Action in Diet-induced Obesity Mice
(Georg Thieme Verlag KgStuttgartAlemanha, 2012)