Buscar
Mostrando ítems 1-10 de 36
Nitosylation: an adverse factor in Hemolytic Uremic Syndrome. Antitoxin effect of Ziziphus mistol Griseb
(Elsevier, 2013-02)
Toxins of Escherichia coli (STEC) causing Uremic Hemolytic Syndrome (UHS) generate oxidative stress in human blood with more production of nitric oxide (NO) than reactive oxygen species (ROS). Shiga toxin (Stx) together ...
Development and characterization of miltefosine-loaded polymeric micelles for cancer treatment
(Elsevier Science, 2017-12)
Miltefosine presents antineoplastic activity but high hemolytic potential. Its use in cancer has been limited to treating cutaneous metastasis of breast cancer. To decrease hemolytic potential, we developed a formulation ...
Absence of interleukin-10 reduces progression of shiga toxin-induced hemolytic uremic syndrome
(Journal of the Serbian Chemical Society, 2021-02)
Hemolytic Uremic Syndrome (HUS), a disease triggered by Shiga toxin (Stx), is characterized by hemolytic anemia, thrombocytopenia and renal failure. The inflammatory response mediated by polymorphonuclear neutrophils (PMNs) ...
Lipid selectivity in novel antimicrobial peptides: Implication on antimicrobial and hemolytic activity
(Elsevier Science, 2017-05)
Antimicrobial peptides (AMPs) are small cationic molecules that display antimicrobial activity against a wide range of bacteria, fungi and viruses. For an AMP to be considered as a therapeutic option, it must have not only ...
Nitrosylation: An adverse factor in Uremic Haemolytic Syndrome. Antitoxin effect of Ziziphus mistol Griseb
(Elsevier, 2013-02)
Toxins of Escherichia coli (STEC) causing Uremic Hemolytic Syndrome (UHS) generate oxidative stress in human blood with more production of nitric oxide (NO) than reactive oxygen species (ROS). Shiga toxin (Stx) together ...
Antiproliferative, cytotoxic and hemolytic activities of a triterpene glycoside from Psolus patagonicus and its desulfated analog
(Karger, 2009-12)
Background: The major triterpene glycoside of the sea cucumber Psolus patagonicus and its desulfated analog were tested for their antiproliferative, cytotoxic and hemolytic activities, and their effect on NF-κB activation. ...
Flunitrazepam partitioning into natural membranes increases surface curvature and alters cellular morphology
(Elsevier Ireland, 2000-12-15)
In recent studies, we showed that flunitrazepam (FNTZ) and other benzodiazepines interact with artificial phospholipid membranes locating at the polar head group region, inducing a membrane expansion, reducing the molecular ...
Effect of Bismuth Hydroxide Gel on Shiga Toxin Producing Escherichia coli
(MedCrave Group, 2018-02)
Shiga toxin-producing Escherichia coli (STEC) are emerging pathogens associatedwith severe and fatal disease in children as Hemolytic Uremic Syndrome (HUS).These bacteria are shedding with feces of cattle contaminating the ...
Comparison of complement system activity amongst wild and domestic animals
(Firenze University Press, 2020-05)
Multiple mechanisms have evolved for the defensive recognition of foreign components, such as microor-ganisms. The majority of immunological studies with vertebrates have been focused on endothermic species, and relatively ...
Prevention of renal damage caused by Shiga toxin type 2: Action of Miglustat on human endothelial and epithelial cells
(Pergamon-Elsevier Science Ltd, 2015-10)
Typical hemolytic uremic syndrome (HUS) is responsible for acute and chronic renal failure in children younger than 5 years old in Argentina. Renal damages have been associated with Shiga toxin type 1 and/or 2 (Stx1, Stx2) ...