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Cyclic-di-GMP signalling regulates motility and biofilm formation in Bordetella bronchiseptica
(Society for General Microbiology, 2013-03-05)
The signalling molecule bis-(39–59)-cyclic-dimeric guanosine monophosphate (c-di-GMP) is a central regulator of diverse cellular functions, including motility, biofilm formation, cell cycle progression and virulence, in ...
A c-di-GMP-Based Switch Controls Local Heterogeneity of Extracellular Matrix Synthesis which Is Crucial for Integrity and Morphogenesis of Escherichia coli Macrocolony Biofilms
(Academic Press Ltd - Elsevier Science Ltd, 2019-11)
The extracellular matrix in macrocolony biofilms of Escherichia coli is arranged in a complex large-scale architecture, with homogenic matrix production close to the surface, whereas zones further below display pronounced ...
Role of nitric oxide/cyclic GMP and cyclic AMP in β3 adrenoceptor-chronotropic response
(Academic Press Ltd - Elsevier Science Ltd, 2006-04)
In this study we determine different signaling pathways involved in â3 adrenoceptor- (â3-AR) dependent frequency stimulation in isolated rodent atria. Promiscuous coupling between different G-proteins and â3-AR could ...
Role of phosphidiesterase and protein kinase G on nitric oxide-induced inhibition of prolactin release from the rat anterior pituitary
(BioScientifica, 2000-08)
Objective: In order to determine the mechanism by which nitric oxide (NO) inhibits prolactin release, we investigated the participation of cGMP-dependent cAMP-phosphodiesterases (PDEs) and protein kinase G (PKG) in this ...
Activation of β 3 adrenergic receptor decreases DNA synthesis in human skin fibroblasts via cyclic GMP/nitric oxide pathway
(Karger, 2005-07)
Background: Evidences have shown that β 1 and β 2 adrenoceptors co-exist in human fibroblasts, but it is not yet clear the functional expression of β 3 adrenoceptor in these cells. The aim of this study was to investigate ...
Role of G-Substrate in the NO/cGMP/PKG Signal Transduction Pathway for Photic Entrainment of the Hamster Circadian Clock
(SAGE Publications, 2021-01)
The mammalian circadian clock at the hypothalamic suprachiasmatic nuclei (SCN) entrains biological rhythms to the 24- h cyclic environment, by encoding light-dark transitions in SCN neurons. Light pulses induce phase shifts ...
Different b-adrenoceptor subtypes coupling to cAMP or NO/cGMP pathways : implications in the relaxant response of rat conductance and resistance vessels
(WileyGrupo de Investigación de Tecnología en Regencia de FarmaciaLondres, Inglaterra, 2022)