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Response to Letter to the Editor “On the targets of fluoxetine”
(Academic Press Ltd - Elsevier Science Ltd, 2016-11)
Immunomodulatory effects of fluoxetine: A new potential pharmacological action for a classic antidepressant drug?
(Academic Press Ltd - Elsevier Science Ltd, 2016-07)
Selective serotonin reuptake inhibitors are frequently used antidepressants. In particular, fluoxetine is usually chosen for the treatment of the symptoms of depression, obsessive-compulsive, panic attack and bulimia ...
Effect of Risperidone and Fluoxetine on the Movement and Neurochemical Changes of Zebrafish
(Scientific Research Publishing, 2012-11)
Brain developmental disorders in humans, including Autism Spectrum Disorders (ASD) and Down’s syndrome, have been linked to increased serotonin levels. This work was designed to study changes in serotonin levels in the ...
Dermestes maculatus (Coleoptera: Dermestidae) development under fluoxetine effect using two drug administration models
(Wiley Blackwell Publishing, Inc, 2021-01)
Fluoxetine is a selective serotonin reuptake inhibitor, commonly used for the treatment of a variety of psychopathological conditions. As such, fluoxetine may be expected to appear in clinical and forensic cases. Dermestes ...
The use of two fly species to detect the anti-depressant Fluoxetine post-mortem (Diptera:Calliphoridae: Lucilia sericata Meigen, Sarcophagidae: Sarcophaga crassipalpis Macquart)
(New York Entomological Society, 2019-11)
The study of insects of forensic interest with the purpose of qualitatively and/or quantitatively detecting toxic substances is called forensic entomotoxicology. The present study was conducted to detect and quantify ...
Fluoxetine potentiation of Omega-3 fatty acid antidepressant effect: evaluating pharmacokinetic and brain fatty acid-related aspects in rodents
(2014-10)
We previously reported that combined fluoxetine administration at antidepressant doses renders additive antidepressant effects, whereas non-antidepressant doses potentiate the omega-3 fatty acid antidepressant effect. In ...
Reserpine-induced depression is associated in female, but not in male, adolescent rats with heightened, fluoxetine-sensitive, ethanol consumption
(Elsevier Science, 2018-08)
Depression usually emerges during adolescence, is significantly more frequent in women, and exhibits comorbidity with alcohol (ethanol) use disorders. Most of the pre-clinical studies assessing the link between depression ...
Chronic treatment with fluoxetine decreases seizure threshold in naïve but not in rats exposed to the learned helplessness paradigm: Correlation with the hippocampal glutamate release
(Pergamon-Elsevier Science Ltd, 2005-06)
The proconvulsive effect of the new generation of antidepressants remains controversial. The authors investigated in naïve rats the effect of chronic treatment with fluoxetine (FLX) on the convulsive threshold and on two ...
Beneficial effect of fluoxetine and sertraline on chronic stress-induced tumor growth and cell dissemination in a mouse model of lymphoma: Crucial role of antitumor immunity
(Frontiers Media S.A., 2018-06)
Clinical data and experimental studies have suggested a relationship between psychosocial factors and cancer prognosis. Both, stress effects on the immune system and on tumor biology were analyzed independently. However, ...
Fluoxetine for the Symptomatic Treatment of Multiple System Atrophy: The MSA-FLUO Trial
(Wiley-liss, div John Wiley & Sons Inc., 2021-07)
Background: There are no effective treatments for multiple system atrophy (MSA). Objective: The objective of this study was to assess the efficacy and safety of the serotonin reuptake inhibitor fluoxetine (40 mg/d) for the ...