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Isoproterenol induces primary loss of dystrophin in rat hearts: correlation with myocardial injury
(WILEY-BLACKWELL, 2008)
The mechanism of isoproterenol-induced myocardial damage is unknown, but a mismatch of oxygen supply vs. demand following coronary hypotension and myocardial hyperactivity is the best explanation for the complex morphological ...
Disruption of sarcolemmal dystrophin and beta-dystroglycan may be a potential mechanism for myocardial dysfunction in severe sepsis
(NATURE PUBLISHING GROUP, 2010)
Evidence from our laboratory has shown alterations in myocardial structure in severe sepsis/septic shock. The morphological alterations are heralded by sarcolemmal damage, characterized by increased plasma membrane ...
Early dystrophin disruption in the pathogenesis of experimental chronic Chagas cardiomyopathy
(ELSEVIER SCIENCE BVAMSTERDAM, 2013-08-02)
Chronic Chagas cardiomyopathy evolves over a long period of time after initial infection by Trypanosoma cruzi. Similarly, a cardiomyopathy appears later in life in muscular dystrophies. This study tested the hypothesis ...
Mialgias post ejercicio como forma de presentación de una distrofinopatía.: Case report.
(Sociedad Médica de Santiago, 2000)
Stem cells from umbilical cord blood do have myogenic potential, with and without differentiation induction in vitro
(2009-01-14)
Abstract
The dystrophin gene, located at Xp21, codifies dystrophin, which is part of a protein complex responsible for the membrane stability of muscle cells. Its absence on muscle causes Duchenne Muscular ...