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Prevalência de resistência transmitida do HIV-1 aos antirretrovirais no Brasil, pré- início de tratamento
(Universidade Federal de São Paulo (UNIFESP), 2011-09-28)
The selection of resistance mutations to antiretroviral drugs after failure of antiretroviral therapy represents a major challenge for decision-making of new therapeutic regimens in the global pandemic. The high genetic ...
Distribuição da frequência de cepas de Mycobacterium tuberculosis multidroga resistentes (MDR) e extensivamente resistentes (XDR) do estado de São Paulo
(Universidade Federal de São Paulo (UNIFESP), 2020-05-06)
Tuberculosis is a disease susceptible to drug treatment, but the incorrect and irregular use of anti-tuberculosis drugs and prolonged treatment created selective conditions that promoted the emergence of resistance or ...
Aspectos epidemiológicos, clínicos, radiológicos e características renotípicas do Mycobacterium tuberculosis associados a fatores de risco para cura da tuberculose multidrogarresistente
(Universidade Federal de São Paulo (UNIFESP), 2017-07-31)
Objective: To identify risk factors among demographic, clinical and radiological variables associated with multidrug-resistant tuberculosis´s cure, abandonment, failure and death after the first treatment, describe the ...
Drogas, sujeito e proibicionismo: uma discussão sobre os modelos de atenção aos usuários de drogasDrugs, subject and prohibition: a discussion about models of care for drug users
(Universidade Estadual Paulista (Unesp), 2016)
Inferences about fitness cost of antiretroviral drug resistance mutations: insights from the mutation dynamics during structured antiretroviral treatment interruption among individuals experiencing virological failure
(Universidade Federal de São Paulo (UNIFESP), 2019-02-22)
This study reviews drug resistance mutation dynamics on both the pol and gag genes among individuals under antiretroviral virological failure who underwent structured treatment interruption (STI). The study involved a ...
Estudo comparativo do efeito da Echinácea purpúrea e sorafenibe em células de adenocarcinoma renal humano em cultura
(Universidade Federal de São Paulo (UNIFESP), 2010-09-29)
Introduction: The renal cell carcinoma (CR) is relatively rare compared to other cancers. One of the most potent tumor mitogen, vascular endothelial growth factor, VEGF is regulated by numerous pathways, especially Ras and ...
Testes conceituais relativos ao conhecimento terapêutico em Pseudomonas aeruginosa produtoras de São Paulo metalo-beta-lactamase (SPM-1)
(Universidade Federal de São Paulo (UNIFESP), 2021)
Objective: Carbapenem-resistant Pseudomonas aeruginosa (CR-PSA) imposes great limitations on empirical therapeutic choices, which are further complicated by metallo-beta-lactamase production. In Brazil, local dissemination ...
Ação reversora in vitro e in vivo do verapamil sobre a resistência de Haemonchus contortus à invermectina
(Universidade Estadual Paulista (Unesp), 2014)