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A new synthesis pathway for colloidal silica spheres coated with crystalline titanium oxide and its comparative cyto- and genotoxic study with titanium oxide nanoparticles in rat osteosarcoma (UMR106) cells
(Elsevier Science, 2013-03)
Spherical particles with an amorphous core of silica and a crystalline shell of titanium oxide (SiO2@TiO2) formed in a three-step procedure, being the last step a mild chemical treatment. SiO2@TiO2 had a shell with pores ...
Antifungal, phyto, cyto, genotoxic and lipophilic properties of three complexes of sulfadimethoxine (HSDM) with Ag(I). Synthesis and characterization of [Ag3SDM(SCN)2]·H2O and [Ag2(SDM)2o-phenanthroline]·H2O
(Pergamon-Elsevier Science Ltd, 2021-02)
Fungal infections are still a major problem. Some limitations of current antifungals (toxicity, fungal resistance) require the search for new drugs. The interest in metal–sulfanilamide derivatives was stimulated by the ...
Copper complex with sulfamethazine and 2,2′-bipyridine supported on mesoporous silica microspheres improves its antitumor action toward human osteosarcoma cells: cyto- and genotoxic effects
(Springer, 2019-02)
Ideal drugs to cure cancer leave normal cells unharmed while selectively turning tumor cells unviable. Several copper complexes have been able to selectively slow down tumor proliferation. We hypothesized that Cu(smz)2(bipy)·H2O ...
Dibucaine in Ionic-Gradient Liposomes: Biophysical, Toxicological, and Activity Characterization
(Elsevier, 2018-09)
Administration of local anesthetics is one of the most effective pain control techniques for postoperative analgesia. However, anesthetic agents easily diffuse into the injection site, limiting the time of anesthesia. One ...
Ecotoxicological evaluation of foundry sands and cosmetic sludges using new earthworm biomarkers
(Springer, 2016-03)
The management and final disposal of industrial wastes are a matter of considerable human concern. The present study evaluates the cyto/genotoxic effects and changes of the coelomic cell formulas exerted by aqueous leachates ...
Cytotoxic activity and genotoxicity of antioxidant WPC-hydrolysates and their probiotics compatibility as Potential Functional Feed Additive
(Elsevier, 2021-06)
Whey protein concentrate (WPC) is produced in large quantities by dairy industry. The enzymatic hydrolysis of WPC can produce antioxidant peptides and therefore, the dairy industry can develop functional additives based ...
Nanoemulsion of Minthostachys verticillata essential oil. In-vitro evaluation of its antibacterial activity
(Elsevier, 2021)
Infectious diseases constitute a problem of great importance for animal and human health, as well as the increasing bacterial resistance to antibiotics. In this context, medicinal plants emerge as an effective alternative ...
Nanoemulsion of Minthostachys verticillata essential oil: In-vitro evaluation of its antibacterial activity
(Elsevier, 2021-01)
Infectious diseases constitute a problem of great importance for animal and human health, as well as the increasing bacterial resistance to antibiotics. In this context, medicinal plants emerge as an effective alternative ...