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Risk Factors for Maternal Chagas Disease and Vertical Transmission in a Bolivian Hospital.
(Oxford University Press, 2021)
BACKGROUND: Vertical transmission of Trypanosoma cruzi infection accounts for a growing proportion of new cases of Chagas disease. Better risk stratification is needed to predict which women are more likely to transmit ...
Use of a novel chagas urine nanoparticle test (chunap) for diagnosis of congenital chagas disease
(Public Library of Science, 2014)
BACKGROUND: Detection of congenital T. cruzi transmission is considered one of the pillars of control programs of Chagas disease. Congenital transmission accounts for 25% of new infections with an estimated 15,000 infected ...
Dr. Luis Dao Lameh first report of congenital ChagasDr. Luis Dao Lameh y el primer reporte de Chagas congénito
(Universidad Centroccidental Lisandro Alvarado, 2018)
Amplicon sequencing reveals complex infection in infants congenitally infected with Trypanosoma cruzi and informs the dynamics of parasite transmission.
(Oxford University Press, 2023)
Congenital transmission of Trypanosoma cruzi is an important source of new Chagas infections worldwide. The mechanisms of congenital transmission remain poorly understood, but there is evidence that parasite factors are ...
Congenital Chagas disease in Santa Cruz Department, Bolivia, is dominated by Trypanosoma cruzi lineage V
(Oxford University Press, 2021)
BACKGROUND: This study identified Trypanosoma cruzi discrete typing units (DTUs) in maternal and infant specimens collected from two hospitals in Bolivia, using conventional genotyping and DTU-specific serotyping. METHODS: ...
Toward Improving Early Diagnosis of Congenital Chagas Disease in an Endemic Setting
(Oxford University Press, 2017)
Background: Congenital Trypanosoma cruzi transmission is now estimated to account for 22% of new infections, representing a significant public health problem across Latin America and internationally. Treatment during infancy ...
Congenital Chagas disease: Updated recommendations for prevention, diagnosis, treatment, and follow-up of newborns and siblings, girls, women of childbearing age, and pregnant women
(Public Library of Science, 2019-10)
Targeted populations for prevention and control of congenital transmission of T. cruziIn order to eliminate congenital transmission of T. cruzi, efforts should be focused on 5 population groups living within or outside of ...
High Prevalence of Congenital Trypanosoma cruzi Infection and Family Clustering in Salta, Argentina
(American Academy of Pediatrics, 2005-06-06)
Objective.Trypanosoma cruzi, the causative agent of Chagas’ disease, is transmitted mainly by insect vectors, but congenital and transfusion-borne infections occasionally occur. The factors that are involved in transmission ...
Higher congenital transmission rate of Trypanosoma cruzi associated with family history of congenital transmission
(Sociedade Brasileira de Medicina Tropical, 2020-03)
Introduction: Congenital transmission (CT) of Trypanosoma cruzi has led to globalization of Chagas disease and its growing relevance as a public health problem. Although the occurrence of CT has been associated with several ...
Congenital Chagas disease involves Trypanosoma cruzi sub-lineage IId in the northwestern province of Salta, Argentina
(Elsevier, 2009-03)
Trypanosoma cruzi is genetically classified into six discrete phylogenetic lineages on the basis of different genetic markers. Identifying lineages circulating among humans in different areas is essential to understand the ...