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Downregulation of ATM Gene and Protein Expression in Canine Mammary Tumors
(2016-11-01)
The ataxia telangiectasia mutated (ATM) gene encodes a protein associated with DNA damage repair and maintenance of genomic integrity. In women, ATM transcript and protein downregulation have been reported in sporadic ...
Immunohistochemical expression of p53 and p63 in adenomas and carcinomas of canine mammary glands
(2012)
Mammary tumors are very common in female dogs and its prognosis varies significantly according to the tumor invasion degree. Myoepithelial layer destruction is considered a differential diagnosis parameter of in situ from ...
Simvastatin modulates beta-catenin/MDR1 expression on spheres derived from CF41.Mg canine mammary carcinoma cells
(Polska Akad Nauk, 2018)
The presence of cancer stem-like cells (CSC) within canine mammary tumors, may explain partly local recurrence and spreading, since their ability to resist conventional antitumor treatments as chemo and radiotherapy. It ...
Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells
(Spandidos Publications Ltd., 2017)
Cyclooxygenase (COX)-2 expression is positively correlated with malignant features in canine mammary carcinomas. Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit COX activity and may therefore possess anticancer ...
Simvastatin modulates β-catenin/MDR1 expression on spheres derived from CF41.Mg canine mammary carcinoma cells
(Polish Academy of Sciences, 2018)
© 2018 Polish Academy of Sciences. All rights reserved. The presence of cancer stem-like cells (CSC) within canine mammary tumors, may explain partly local recurrence and spreading, since their ability to resist conventional ...
Cytologic analysis of the mammary papillar discharge in a canine micropapillary carcinoma
(American Society for Veterinary Clinical Pathology., 2015)
This is a report on the cytologic analysis of the mammary papillar discharge in a 7-year-old female Doberman dog with an invasive micropapillary carcinoma. Cytologic evaluation of nipple discharge is a well-known method ...
Evaluation of vascular endothelial growth factor gene and protein expression in canine metastatic mammary carcinomas
(Wiley-Blackwell, 2016-11-01)
Vascular endothelial growth factor (VEGF) is a potent angiogenic factor that could be associated with the induction of endothelial cell proliferation and metastasis. In this study, we evaluated VEGF gene and protein ...
Microvessel density assessment in canine mammary carcinomas as a predictive factor for metronomic chemotherapy
(2019-01-01)
The canine mammary tumor is the neoplasia that most commonly affects intact female dogs (not spayed) in routine veterinary practice. Canine mammary tumor therapy is a challenge because only few effective treatments have ...
Combination of suicide and cytokine gene therapies as surgery adjuvant for canine mammary carcinoma
(MDPI, 2018-09)
The incidence of canine mammary carcinoma varies with age, breed, and spay status, being among the main tumors appearing in intact female dogs. Thirty-six canine mammary carcinoma patients received injections of canine ...