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Imaging single-channel calcium microdomains by total internal reflection microscopy
(Sociedad de Biología de Chile, 2004)
Voltage-controlled gating in a large conductance Ca2+-sensitive K(+)channel (hslo)
(NATL ACAD SCIENCES, 1997-05-13)
Large conductance calcium- and voltage-sensitive K+ (MaxiK) channels share properties of voltage- and ligand-gated ion channels. In voltage-gated channels, membrane depolarization promotes the displacement of charged ...
Differential effects of beta 1 and beta 2 subunits on BK channel activity
(ROCKEFELLER UNIV PRESS, 2005-04)
High conductance, calcium- and voltage-activated potassium (BK) channels are widely expressed in mammals. In some tissues, the biophysical properties of BK channels are highly affected by coexpression of regulatory (beta) ...
Spontaneous activity of the light-dependent channel irreversibly induced in excised patches from Limulus ventral photoreceptors
(Springer-Verlag, 1992)
We have studied the properties of membrane patches excised from the transducing lobe of Limulus ventral photoreceptors. If patches are excised into an "internal" solution that resembles the ionic composition of the cytoplasm, ...
Role of the S4 segment in a voltage-dependent calcium-sensitive potassium (hSlo) channel
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 1998-12-04)
We investigated the role of individual charged residues of the S4 region of a MaxiK channel (hSlo) in channel gating, We measured macroscopic currents induced by wild type (WT) and point mutants of hSlo in inside-out ...
Marine Toxins Targeting Ion Channels
(Molecular Diversity Preservation International, 2006-04)
This introductory minireview points out the importance of ion channels for cell communication. The basic concepts on the structure and function of ion channels triggered by membrane voltage changes, the so-called voltage-gated ...
Single Ca2+-activated Cl- channel currents recorded from toad olfactory cilia
(Biomed Central, 2016)
Background: Odor transduction, occurring in the chemosensory cilia of vertebrate olfactory sensory neurons, is triggered by guanosine triphosphate-coupled odor receptors and mediated by a cyclic adenosine monophosphate ...
Coupling of voltage-dependent gating and Ba++ block in the high-conductance, Ca++-activated K+ channel
(1987)
Voltage-dependent Ca++-activated K+ channels from rat skeletal muscle were reconstituted into planar lipid bilayers, and the kinetics of block of single channels by Ba++ were studied. The Ba++ association rate varies ...
Identification of a sphingosine-sensitive Ca2+ channel in the plasma membrane of Leishmania mexicana
(Biochemical and Biophysical Research Communications, 2013)