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Molecular insights to alkaline based bio-fabrication of silver nanoparticles for inverse cytotoxicity and enhanced antibacterial activity
(Elsevier Ltd, 2018)
© 2018 Elsevier B.V. High demand for silver nanoparticles due to their extensive applications in different field has raised need of eco-friendly green synthesis with determined biomedical effects. This study proposes a ...
Two new hygroline and tropane alkaloids isolated from schizanthus hookeri and S. tricolor (Solanaceae)
(Natural Product Incorporation, 2017)
Two new hygroline and tropane alkaloids, 4-hydroxybenzenepropanoylhygroline (1) and 3α,4β-dihydroxy-6β-angeloyoxytropane (2) have been isolated from the aerial parts of Schizanthus hookeri and S. tricolor, respectively, ...
Antibacterial activity and human cell cytotoxic of cobalt (III) complexes with 1,10-phenanthroline and carbohydrate ligands
(Sociedad Chilena de Química, 2017)
The mononuclear cobalt (III) complex derived from 1,10-phenanthroline with lactose [Co(phen)(2)lactose]Cl-2 center dot 3H(2)O (1) has been prepared and its properties have been compared with the sucrose complex ...
Cytotoxic organometallic [Ru(η6-anethole)(en)(X)]PF6 (X = Br or I) complexes: Synthesis, characterization and in vitro biological evaluation
(Elsevier B.V., 2017)
Two new organometallic compounds with the general formula [Ru(eta(6)-anethole)(en)(MPF6, where X = Br (5) or I (6) and en = ethylenediamine, were synthesized and fully characterized using standard techniques (NMR, MS and ...
Facing chagas' disease: Trypanocidal properties of new coumarinchalcone scaffolds
(Bentham Science Publishers B.V., 2016)
© 2016 Bentham Science Publishers. With the aim of finding new chemical entities based on coumarin and chalcone scaffolds, new hybrid compounds 2-5 were designed and synthesized. The trypanocidal activity of these compounds ...
Facing Chagas' Disease: Trypanocidal Properties of New Coumarin-chalcone Scaffolds
(Bentham Science, 2016)
With the aim of finding new chemical entities based on coumarin and chalcone scaffolds, new hybrid compounds 2-5 were designed and synthesized. The trypanocidal activity of these compounds was tested against the epimastigote, ...
A systematic study of antibacterial silver nanoparticles: efficiency, enhanced permeability, and cytotoxic effects
(Kluwer Academic Publishers, 2014)
We report here a systematic study of the antibacterial behavior of silver nanoparticles coated with fatty acids (oleic: AgNP-O, linoleic: AgNP-L, and palmitic acids: AgNP-P) in water. We have found remarkable differences ...
Biological activities and metabolites from Trevoa trinervis Miers
(1997)
Chilean folklore medicine uses Trevoa trinervis Miers. (Rhamnaceae), 'trevo', for the treatment of inflammation caused by wounds and burns. The antiinflammatory and antipyretic activities of crude methanol, aqueous and ...
Topical Anti-inflammatory Activity of New Hybrid Molecules of Terpenes and Synthetic Drugs
(MDPI AG, 2015)
The aim of the study was to assess changes in the activity of anti-inflammatory terpenes from Chilean medicinal plants after the formation of derivatives incorporating synthetic anti-inflammatory agents. Ten new hybrid ...
Hypoxic Melanoma Cells Deliver microRNAs to Dendritic Cells and Cytotoxic T Lymphocytes through Connexin-43 Channels
(MDPI, 2020)
Alterations in microRNA (miRNA) profiles, induced by tumor microenvironment stressors, like hypoxia, allow cancer cells to acquire immune-resistance phenotypes. Indeed, hypoxia-induced miRNAs have been implicated in cancer ...