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Organic solvent adaptation of Gram positive bacteria: applications and biotechnological potentials
(Pergamon-Elsevier Science Ltd, 2011-01)
Organic-solvent-tolerant bacteria are considered extremophiles with different tolerance levels that change among species and strains, but also depend on the inherent toxicity of the solvent. Extensive studies to understand ...
Activity and stability of lipase preparations from Penicillium corylophilum: Potential use in biocatalysis
(Wiley-VCH, 2014-11)
Biocatalysts with lipase activity were produced by Penicillium corylophilum under basal and olive oil-induced conditions. In the presence of olive oil, both the extracellular and the mycelium-bound lipase activities were ...
Bile acids: Lipase-catalyzed synthesis of new hyodeoxycholic acid derivatives
(Elsevier Science Inc, 2018-12)
In this work we present an efficient, environmentally friendly approach to the synthesis of a series of hyodeoxycholic acid derivatives applying Biocatalysis. Fifteen acetyl and ester derivatives, twelve of them new, were ...
Cell immobilization strategies for biotransformations
(Elsevier, 2022-02)
This review deals with up-to-date applications related to cell immobilization used for varied biocatalytic purposes in diverse areas ranging from the food and dairy industry, synthesis of added value products such as ...
Chemoenzymatic synthesis of hygromycin aminocyclitol moiety and its C2 epimer
(Wiley VCH Verlag, 2018-11-29)
This manuscript describes the enantioselective synthesis of the aminocyclitol moiety of the antibiotic hygromycin A in eight steps and 39 % overall yield from a non-chiral starting material. The sequence made use of an ...
Biotransformation of 5´-O-β-D-galactosyl-floxuridine by immobilized β-galactosidase from Kocuria rhizophila
(Elsevier Science Sa, 2018-10)
5-fluorouracil-2’-deoxyriboside (FUdR), an antimetabolite known as floxuridine, is a halogenated nucleoside extensively used in the clinical treatment of colon carcinoma and hepatic metastases. This drug presents low ...
An update of biocatalytic selective acylation and deacylation of monosaccharides
(Royal Society of Chemistry, 2016-03)
Partially acylated monosaccharides (PAMs) exhibit diverse and interesting applications but due to their polyhydroxylated nature, their synthesis requires regio- and stereoselective reactions. These features are provided ...
An enzymatic alternative for the synthesis of nucleoside 5′-monophosphates
(Elsevier Science Inc, 2018-04)
A new procedure was carried out for the synthesis of nucleoside 5′-monophosphates, involving the use of two enzymes. The first step applied phospholipase D from Streptomyces netropsis and phosphatidylcholine as phosphatidyl ...
Deracemisation processes employing organocatalysis and enzyme catalysis
(Wiley VCH Verlag, 2020-03)
Deracemisation methods have demonstrated their importance in the preparation of chiral compounds in the last few years. In order to resolve a racemic mixture in a dynamic sense, one enantiomer of the starting material can ...